TY - JOUR
T1 - Two cases of stage IV gastric cancer responding to chemotherapy and leading to pathological complete response
AU - Kubota, Tetsushi
AU - Kagawa, Shunsuke
AU - Kikuchi, Satoru
AU - Kuroda, Shinji
AU - Nishizaki, Masahiko
AU - Fujiwara, Toshiyoshi
PY - 2014/11
Y1 - 2014/11
N2 - Case 1: A 76-year-old man presented with advanced gastric cancer in the esophagogastric junction with para-aortic lymph node metastasis (HER2 positive CT4N1M1 [LYM], cStage IV). After 3 courses of chemotherapy consisting of S-1+docetaxel + trastuzumab were completed, we performed surgery. No cancer cells were revealed during histopathological examination, indicating pathological complete response (pCR). At present, 12 months after treatment, the patient is well, with no signs of recurrence. Case 2: A 74-year-old man presented with advanced gastric cancer with peritoneal metastasis (cT4b [Panc] N1M1 [P], cStage IV). After 2 courses of chemotherapy consisting of S-1+CDDP were completed, we performed surgery. Histopathological examination revealed no cancer cells, indicating pCR. At present, 13 months after treatment, the patient is incident-free, with no signs of recurrence.
AB - Case 1: A 76-year-old man presented with advanced gastric cancer in the esophagogastric junction with para-aortic lymph node metastasis (HER2 positive CT4N1M1 [LYM], cStage IV). After 3 courses of chemotherapy consisting of S-1+docetaxel + trastuzumab were completed, we performed surgery. No cancer cells were revealed during histopathological examination, indicating pathological complete response (pCR). At present, 12 months after treatment, the patient is well, with no signs of recurrence. Case 2: A 74-year-old man presented with advanced gastric cancer with peritoneal metastasis (cT4b [Panc] N1M1 [P], cStage IV). After 2 courses of chemotherapy consisting of S-1+CDDP were completed, we performed surgery. Histopathological examination revealed no cancer cells, indicating pCR. At present, 13 months after treatment, the patient is incident-free, with no signs of recurrence.
KW - Gastric cancer
KW - Neoadjuvant chemotherapy
KW - Pathological complete response
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M3 - Article
C2 - 25731505
AN - SCOPUS:84949217431
SN - 0385-0684
VL - 41
SP - 2308
EP - 2310
JO - Japanese Journal of Cancer and Chemotherapy
JF - Japanese Journal of Cancer and Chemotherapy
IS - 12
ER -
