Abstract
We report two patients with spinocerebellar ataxia (SCA) with cranial and spinal motor neuron involvement. They initially presented with cerebellar ataxia, followed by bulbar palsy and limb motor neuron sign. One of the patients had a brother with allied disorder. SCA type 1 (SCA1), SCA3 and SCA6 have been reported to involve the motor neuron system, but they were excluded by DNA analyses in the present two patients. These two patients may form a distinct disease entity among SCAs.
Original language | English |
---|---|
Pages (from-to) | 751-756 |
Number of pages | 6 |
Journal | Internal Medicine |
Volume | 46 |
Issue number | 11 |
DOIs | |
Publication status | Published - Jun 1 2007 |
Keywords
- Bulbar palsy
- MRI
- Motor neuron disease
- Spinocerebellar ataxia
- Tongue atrophy
ASJC Scopus subject areas
- Internal Medicine