Two cases of spinocerebellar ataxia accompanied by involvement of the skeletal motor neuron system and bulbar palsy

Yasuyuki Ohta, Takeshi Hayashi, Makiko Nagai, Miyuki Okamoto, Shoko Nagotani, Isao Nagano, Nobuhiko Ohmori, Yasushi Takehisa, Tetsuro Murakami, Mikio Shoji, Tatsushi Kamiya, Koji Abe

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

We report two patients with spinocerebellar ataxia (SCA) with cranial and spinal motor neuron involvement. They initially presented with cerebellar ataxia, followed by bulbar palsy and limb motor neuron sign. One of the patients had a brother with allied disorder. SCA type 1 (SCA1), SCA3 and SCA6 have been reported to involve the motor neuron system, but they were excluded by DNA analyses in the present two patients. These two patients may form a distinct disease entity among SCAs.

Original languageEnglish
Pages (from-to)751-756
Number of pages6
JournalInternal Medicine
Volume46
Issue number11
DOIs
Publication statusPublished - Jun 1 2007

Keywords

  • Bulbar palsy
  • MRI
  • Motor neuron disease
  • Spinocerebellar ataxia
  • Tongue atrophy

ASJC Scopus subject areas

  • Internal Medicine

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    Ohta, Y., Hayashi, T., Nagai, M., Okamoto, M., Nagotani, S., Nagano, I., Ohmori, N., Takehisa, Y., Murakami, T., Shoji, M., Kamiya, T., & Abe, K. (2007). Two cases of spinocerebellar ataxia accompanied by involvement of the skeletal motor neuron system and bulbar palsy. Internal Medicine, 46(11), 751-756. https://doi.org/10.2169/internalmedicine.46.6261