Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors

Daisuke Takabatake, Naruto Taira, Kenjiro Aogi, Shozo Ohsumi, Shigemitsu Takashima, Takeshi Inoue, Rieko Nishimura

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We report two cases of occult breast cancer in which masses were completely nonpalpable and positron emission tomography-computed tomography (PET-CT) was extremely helpful in identifying the primary tumor. Case 1 involved a 56-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on excisional biopsy, axillary lymph node metastasis of breast cancer was suspected but an obvious primary tumor in the breast was not identifiable on mammography, contrast-enhanced CT, or ultrasonography. Faint accumulation of fluorodeoxyglucose (FDG) was noted only on PET-CT, so the site was considered to be the primary site, and operation was performed. As a result of postoperative pathological examination, ductal carcinoma in-situ (DCIS) was diagnosed. Case 2 involved a 55-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on the excisional biopsy, axillary lymph node metastasis of breast cancer was suspected. In this case as well, an obvious primary tumor was not identifiable with palpation or mammography. On PET-CT, faint accumulation of FDG was noted in the vicinity of the CD regions, or upper and lower outer quadrants. When contrast-enhanced CT and ultrasonography were performed, a faint nodular opacity less than 1 cm in size corresponding to this site was found and diagnosed as the primary site, operation was subsequently performed. Pathologic diagnosis indicated invasive cancer. PET-CT is a helpful option for the diagnosis of occult breast cancer with primary sites that conventional imaging studies have difficulty identifying.

Original languageEnglish
Pages (from-to)181-184
Number of pages4
JournalBreast Cancer
Volume15
Issue number2
DOIs
Publication statusPublished - Apr 2008
Externally publishedYes

Fingerprint

Breast Neoplasms
Lymph Nodes
Axilla
Mammography
Neoplasms
Ultrasonography
Neoplasm Metastasis
Biopsy
Carcinoma, Intraductal, Noninfiltrating
Palpation
Positron Emission Tomography Computed Tomography

Keywords

  • Breast cancer
  • Occult cancer
  • PET

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)
  • Medicine(all)

Cite this

Takabatake, D., Taira, N., Aogi, K., Ohsumi, S., Takashima, S., Inoue, T., & Nishimura, R. (2008). Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors. Breast Cancer, 15(2), 181-184. https://doi.org/10.1007/s12282-007-0027-7

Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors. / Takabatake, Daisuke; Taira, Naruto; Aogi, Kenjiro; Ohsumi, Shozo; Takashima, Shigemitsu; Inoue, Takeshi; Nishimura, Rieko.

In: Breast Cancer, Vol. 15, No. 2, 04.2008, p. 181-184.

Research output: Contribution to journalArticle

Takabatake, D, Taira, N, Aogi, K, Ohsumi, S, Takashima, S, Inoue, T & Nishimura, R 2008, 'Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors', Breast Cancer, vol. 15, no. 2, pp. 181-184. https://doi.org/10.1007/s12282-007-0027-7
Takabatake, Daisuke ; Taira, Naruto ; Aogi, Kenjiro ; Ohsumi, Shozo ; Takashima, Shigemitsu ; Inoue, Takeshi ; Nishimura, Rieko. / Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors. In: Breast Cancer. 2008 ; Vol. 15, No. 2. pp. 181-184.
@article{1dc6151da83b4952bc4d97c94864cc16,
title = "Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors",
abstract = "We report two cases of occult breast cancer in which masses were completely nonpalpable and positron emission tomography-computed tomography (PET-CT) was extremely helpful in identifying the primary tumor. Case 1 involved a 56-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on excisional biopsy, axillary lymph node metastasis of breast cancer was suspected but an obvious primary tumor in the breast was not identifiable on mammography, contrast-enhanced CT, or ultrasonography. Faint accumulation of fluorodeoxyglucose (FDG) was noted only on PET-CT, so the site was considered to be the primary site, and operation was performed. As a result of postoperative pathological examination, ductal carcinoma in-situ (DCIS) was diagnosed. Case 2 involved a 55-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on the excisional biopsy, axillary lymph node metastasis of breast cancer was suspected. In this case as well, an obvious primary tumor was not identifiable with palpation or mammography. On PET-CT, faint accumulation of FDG was noted in the vicinity of the CD regions, or upper and lower outer quadrants. When contrast-enhanced CT and ultrasonography were performed, a faint nodular opacity less than 1 cm in size corresponding to this site was found and diagnosed as the primary site, operation was subsequently performed. Pathologic diagnosis indicated invasive cancer. PET-CT is a helpful option for the diagnosis of occult breast cancer with primary sites that conventional imaging studies have difficulty identifying.",
keywords = "Breast cancer, Occult cancer, PET",
author = "Daisuke Takabatake and Naruto Taira and Kenjiro Aogi and Shozo Ohsumi and Shigemitsu Takashima and Takeshi Inoue and Rieko Nishimura",
year = "2008",
month = "4",
doi = "10.1007/s12282-007-0027-7",
language = "English",
volume = "15",
pages = "181--184",
journal = "Breast Cancer",
issn = "1340-6868",
publisher = "Springer Japan",
number = "2",

}

TY - JOUR

T1 - Two cases of occult breast cancer in which PET-CT was helpful in identifying primary tumors

AU - Takabatake, Daisuke

AU - Taira, Naruto

AU - Aogi, Kenjiro

AU - Ohsumi, Shozo

AU - Takashima, Shigemitsu

AU - Inoue, Takeshi

AU - Nishimura, Rieko

PY - 2008/4

Y1 - 2008/4

N2 - We report two cases of occult breast cancer in which masses were completely nonpalpable and positron emission tomography-computed tomography (PET-CT) was extremely helpful in identifying the primary tumor. Case 1 involved a 56-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on excisional biopsy, axillary lymph node metastasis of breast cancer was suspected but an obvious primary tumor in the breast was not identifiable on mammography, contrast-enhanced CT, or ultrasonography. Faint accumulation of fluorodeoxyglucose (FDG) was noted only on PET-CT, so the site was considered to be the primary site, and operation was performed. As a result of postoperative pathological examination, ductal carcinoma in-situ (DCIS) was diagnosed. Case 2 involved a 55-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on the excisional biopsy, axillary lymph node metastasis of breast cancer was suspected. In this case as well, an obvious primary tumor was not identifiable with palpation or mammography. On PET-CT, faint accumulation of FDG was noted in the vicinity of the CD regions, or upper and lower outer quadrants. When contrast-enhanced CT and ultrasonography were performed, a faint nodular opacity less than 1 cm in size corresponding to this site was found and diagnosed as the primary site, operation was subsequently performed. Pathologic diagnosis indicated invasive cancer. PET-CT is a helpful option for the diagnosis of occult breast cancer with primary sites that conventional imaging studies have difficulty identifying.

AB - We report two cases of occult breast cancer in which masses were completely nonpalpable and positron emission tomography-computed tomography (PET-CT) was extremely helpful in identifying the primary tumor. Case 1 involved a 56-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on excisional biopsy, axillary lymph node metastasis of breast cancer was suspected but an obvious primary tumor in the breast was not identifiable on mammography, contrast-enhanced CT, or ultrasonography. Faint accumulation of fluorodeoxyglucose (FDG) was noted only on PET-CT, so the site was considered to be the primary site, and operation was performed. As a result of postoperative pathological examination, ductal carcinoma in-situ (DCIS) was diagnosed. Case 2 involved a 55-year-old woman with enlarged lymph nodes 3 cm in size in the axilla. Based on the excisional biopsy, axillary lymph node metastasis of breast cancer was suspected. In this case as well, an obvious primary tumor was not identifiable with palpation or mammography. On PET-CT, faint accumulation of FDG was noted in the vicinity of the CD regions, or upper and lower outer quadrants. When contrast-enhanced CT and ultrasonography were performed, a faint nodular opacity less than 1 cm in size corresponding to this site was found and diagnosed as the primary site, operation was subsequently performed. Pathologic diagnosis indicated invasive cancer. PET-CT is a helpful option for the diagnosis of occult breast cancer with primary sites that conventional imaging studies have difficulty identifying.

KW - Breast cancer

KW - Occult cancer

KW - PET

UR - http://www.scopus.com/inward/record.url?scp=58949092027&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=58949092027&partnerID=8YFLogxK

U2 - 10.1007/s12282-007-0027-7

DO - 10.1007/s12282-007-0027-7

M3 - Article

C2 - 18274836

AN - SCOPUS:58949092027

VL - 15

SP - 181

EP - 184

JO - Breast Cancer

JF - Breast Cancer

SN - 1340-6868

IS - 2

ER -