Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Yasuhiro Takahara, Keiichiro Nishida, Hirotaka Nakashima, Nobuaki Ochi, Yoichiro Uchida, Hisayoshi Kato, Satoru Itani, Makoto Nakamura, Yuichi Iwasaki, Yoshitaka Tsujimura

Research output: Contribution to journalArticle

Abstract

High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.

Original languageEnglish
Pages (from-to)537-542
Number of pages6
JournalActa medica Okayama
Volume73
Issue number6
Publication statusPublished - 2019
Externally publishedYes

Keywords

  • Biologic DMARD
  • High tibial osteotomy
  • Knee surgery
  • Rheumatoid arthritis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Takahara, Y., Nishida, K., Nakashima, H., Ochi, N., Uchida, Y., Kato, H., Itani, S., Nakamura, M., Iwasaki, Y., & Tsujimura, Y. (2019). Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs. Acta medica Okayama, 73(6), 537-542.