Abstract
The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.
| Original language | English |
|---|---|
| Pages (from-to) | 300-303 |
| Number of pages | 4 |
| Journal | Zeitschrift fur Naturforschung - Section C Journal of Biosciences |
| Volume | 55 |
| Issue number | 3-4 |
| Publication status | Published - Mar 2000 |
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Keywords
- Antinematodal Compounds
- Bursaphelenchus xylophilus
- Knema hookeriana
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Biochemistry
Cite this
Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant. / Alen, Yohannes; Nakajima, Shuhei; Nitoda, Teruhiko; Baba, Naomichi; Kanzaki, Hiroshi; Kawazu, Kazuyoshi.
In: Zeitschrift fur Naturforschung - Section C Journal of Biosciences, Vol. 55, No. 3-4, 03.2000, p. 300-303.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant
AU - Alen, Yohannes
AU - Nakajima, Shuhei
AU - Nitoda, Teruhiko
AU - Baba, Naomichi
AU - Kanzaki, Hiroshi
AU - Kawazu, Kazuyoshi
PY - 2000/3
Y1 - 2000/3
N2 - The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.
AB - The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.
KW - Antinematodal Compounds
KW - Bursaphelenchus xylophilus
KW - Knema hookeriana
UR - http://www.scopus.com/inward/record.url?scp=0034066086&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034066086&partnerID=8YFLogxK
M3 - Article
C2 - 10817224
AN - SCOPUS:0034066086
VL - 55
SP - 300
EP - 303
JO - Zeitschrift fur Naturforschung. Section C: Biosciences
JF - Zeitschrift fur Naturforschung. Section C: Biosciences
SN - 0939-5075
IS - 3-4
ER -