Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant

Yohannes Alen; Shuhei Nakajima; Teruhiko Nitoda; Naomichi Baba; Hiroshi Kanzaki; Kazuyoshi Kawazu

doi:10.1515/znc-2000-3-426

Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant

Yohannes Alen, Shuhei Nakajima, Teruhiko Nitoda, Naomichi Baba, Hiroshi Kanzaki, Kazuyoshi Kawazu

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.

Original language	English
Pages (from-to)	300-303
Number of pages	4
Journal	Zeitschrift fur Naturforschung - Section C Journal of Biosciences
Volume	55
Issue number	3-4
DOIs	https://doi.org/10.1515/znc-2000-3-426
Publication status	Published - 2000

Keywords

Antinematodal Compounds
Bursaphelenchus xylophilus
Knema hookeriana

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1515/znc-2000-3-426

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abstract = "The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.",

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doi = "10.1515/znc-2000-3-426",

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T1 - Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant

AU - Alen, Yohannes

AU - Nakajima, Shuhei

AU - Nitoda, Teruhiko

AU - Baba, Naomichi

AU - Kanzaki, Hiroshi

AU - Kawazu, Kazuyoshi

PY - 2000

Y1 - 2000

N2 - The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.

AB - The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.

KW - Antinematodal Compounds

KW - Bursaphelenchus xylophilus

KW - Knema hookeriana

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JF - Zeitschrift fur Naturforschung. Teil C: Biochemie, Biophysik, Biologie, Virologie

SN - 0939-5075

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ER -

Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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