Abstract
The activity-guided chromatographic purification of the methanol extract of Knema hookeriana, using pine wood nematodes Bursaphelenchus xylophilus has successfully led to the isolation and characterization of two phenolic antinematodal compounds with minimum effective dose (MED) of 4.5 and 20 μg/cotton ball (μg/bl.) or 0.018 and 0.073 μM/cotton ball (μM/bl.), respectively. Based on their chemical and spectral properties, these compounds were determined to be 3-undecylphenol (1) and 3-(8Z-tridecenyl)-phenol (2). These compounds were isolated for the first time from this species, and 2 seems to be a novel compound.
| Original language | English |
|---|---|
| Pages (from-to) | 300-303 |
| Number of pages | 4 |
| Journal | Zeitschrift fur Naturforschung - Section C Journal of Biosciences |
| Volume | 55 |
| Issue number | 3-4 |
| Publication status | Published - Mar 1 2000 |
Keywords
- Antinematodal Compounds
- Bursaphelenchus xylophilus
- Knema hookeriana
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
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Cite this
Alen, Y., Nakajima, S., Nitoda, T., Baba, N., Kanzaki, H., & Kawazu, K. (2000). Two antinematodal phenolics from Knema hookeriana, a Sumatran rainforest plant. Zeitschrift fur Naturforschung - Section C Journal of Biosciences, 55(3-4), 300-303.