Twenty-year follow-up of the first bilateral living-donor lobar lung transplantation in Japan

Masamichi Komatsu, Hiroshi Yamamoto, Toshitaka Shomura, Kei Sonehara, Takashi Ichiyama, Kazuhisa Urushihata, Atsuhito Ushiki, Masanori Yasuo, Toshihide Wakamatsu, Seiichiro Sugimoto, Takahiro Oto, Hiroshi Date, Tomonobu Koizumi, Masayuki Hanaoka, Keishi Kubo

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Abstract

Patients with end-stage lung disease can undergo living-donor lobar lung transplantation (LDLLT), with survival rates improving every year. We herein report the 20-year follow-up findings of the first patient who underwent LDLLT in Japan. A 24-year-old woman with primary ciliary dyskinesia became ventilator-dependent after severe respiratory failure and right-sided heart failure following repeated respiratory infections. In 1998, she underwent LDLLT and received her sister’s right lower lobe and her mother’s left lower lobe. Although the patient required 21 hospitalizations and developed unilateral bronchiolitis obliterans syndrome, she is in good physical condition and lives without restriction at 20 years after undergoing LDLLT.

Original languageEnglish
Pages (from-to)3133-3137
Number of pages5
JournalInternal Medicine
Volume58
Issue number21
DOIs
Publication statusPublished - 2019

Keywords

  • Cadaveric lung transplantation
  • Living-donor lobar lung transplantation
  • Long-term outcomes
  • Primary ciliary dyskinesia

ASJC Scopus subject areas

  • Internal Medicine

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  • Cite this

    Komatsu, M., Yamamoto, H., Shomura, T., Sonehara, K., Ichiyama, T., Urushihata, K., Ushiki, A., Yasuo, M., Wakamatsu, T., Sugimoto, S., Oto, T., Date, H., Koizumi, T., Hanaoka, M., & Kubo, K. (2019). Twenty-year follow-up of the first bilateral living-donor lobar lung transplantation in Japan. Internal Medicine, 58(21), 3133-3137. https://doi.org/10.2169/internalmedicine.3160-19