Tumor formation on the lower eye lid and self-healing papules on the face in a patient with mycosis fungoides

A 59-year-old man presented with a few year history of multiple erythematous and depigmented patches over the entire body, and was treated with topical steroids. Subsequently, he developed a tumor on his lower eyelid and visited our department Histopathology of a biopsy specimen from the tumor revealed medium to large lymphoid cells throughout the dermis and lymphoid epidermotropism. The patient was diagnosed as stage IIB mycosis fungoides. The tumor was diminished by local radiation therapy and the patches were treated with PUVA therapy. The papules on his face evolved and involuted spontaneously. The development of a tumor and concomitant lymphomatoid papulosis in early stage mycosis fungoides were characteristic. As the large cells of the tumor on the eyelid and papules on the face were positive for CD30, we interpreted the changes of CD30-positive lymphoproliferative disorder as associated with mycosis fungoides.