Trends in incidence and mortality of tuberculosis in Japan: A population-based study, 1997-2016

H. Hagiya, T. Koyama, Y. Zamami, Y. Minato, Y. Tatebe, N. Mikami, Y. Teratani, A. Ohshima, K. Shinomiya, Y. Kitamura, T. Sendo, S. Hinotsu, K. Tomono, M. R. Kano

Research output: Contribution to journalArticle

Abstract

Japan is still a medium-burden tuberculosis (TB) country. We aimed to examine trends in newly notified active TB incidence and TB-related mortality in the last two decades in Japan. This is a population-based study using Japanese Vital Statistics and Japan Tuberculosis Surveillance from 1997 to 2016. We determined active TB incidence and mortality rates (per 100 000 population) by sex, age and disease categories. Joinpoint regression was applied to calculate the annual percentage change (APC) in age-adjusted mortality rates and to identify the years showing significant trend changes. Crude and age-adjusted incidence rates reduced from 33.9 to 13.9 and 37.3 to 11.3 per 100 000 population, respectively. Also, crude and age-adjusted mortality rates reduced from 2.2 to 1.5 and 2.8 to 1.0 per 100 000 population, respectively. Average APC in the incidence and mortality rates showed significant decline both in men ('6.2% and '5.4%, respectively) and women ('5.7% and '4.6%, respectively). Age-specific analysis demonstrated decreases in incidence and mortality rates for every age category, except for the incidence trend in the younger population. Although trends in active TB incidence and mortality rates in Japan have favourably decreased, the rate of decline is far from achieving TB elimination by 2035.

Original languageEnglish
JournalEpidemiology and Infection
DOIs
Publication statusAccepted/In press - Jan 1 2018

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Japan
Tuberculosis
Mortality
Incidence
Population
Vital Statistics

Keywords

  • Incidence
  • mortality
  • trend analysis
  • tuberculosis

ASJC Scopus subject areas

  • Epidemiology
  • Infectious Diseases

Cite this

Trends in incidence and mortality of tuberculosis in Japan : A population-based study, 1997-2016. / Hagiya, H.; Koyama, T.; Zamami, Y.; Minato, Y.; Tatebe, Y.; Mikami, N.; Teratani, Y.; Ohshima, A.; Shinomiya, K.; Kitamura, Y.; Sendo, T.; Hinotsu, S.; Tomono, K.; Kano, M. R.

In: Epidemiology and Infection, 01.01.2018.

Research output: Contribution to journalArticle

Hagiya, H. ; Koyama, T. ; Zamami, Y. ; Minato, Y. ; Tatebe, Y. ; Mikami, N. ; Teratani, Y. ; Ohshima, A. ; Shinomiya, K. ; Kitamura, Y. ; Sendo, T. ; Hinotsu, S. ; Tomono, K. ; Kano, M. R. / Trends in incidence and mortality of tuberculosis in Japan : A population-based study, 1997-2016. In: Epidemiology and Infection. 2018.
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