Trends in axillary treatment for breast cancer patients undergoing sentinel lymph node biopsy as determined by a questionnaire from the Japanese Breast Cancer Society

Shigeru Imoto, Chikako Yamauchi, Yoshifumi Komoike, Koichiro Tsugawa, Daisuke Yotsumoto, Noriaki Wada, Takayuki Ueno, Mari S. Oba, Tadahiko Shien, Sadatoshi Sugae, Hitoshi Tsuda, Kimiyasu Yoneyama

Research output: Contribution to journalArticle

Abstract

Background: Sentinel lymph node biopsy (SLNB) alone has been compared with SLNB followed by axillary lymph node dissection (ALND) in sentinel lymph node (SLN)-positive breast cancer patients in randomized phase III trials: the addition of ALND did not further improve the patient’s outcome. However, there is still some controversy, regarding the clinical application of SLNB alone. To identify the optimal axillary treatment in the era of SLNB, the Japanese Breast Cancer Society conducted a group study of SLNB in 2014. Methods: A questionnaire on axillary surgery and radiation therapy was sent to 432 Japanese institutes in December 2014, and 309 (72 %) completed the questionnaire. Results: SLNB was performed at 98 % of the institutes, and 77 % offered irradiation for cancer treatment. Regarding breast-conserving surgery (BCS), SLNB alone was indicated at 41 % of the institutes in the cases of SLN with micrometastases. However, in the cases of SLN with macrometastases, ALND was performed at 64 %. The proportion of ALND seemed to be higher in total mastectomy than in BCS regardless of the SLN-positive status. In the cases of SLN with micrometastases, the radiation field was localized in the conserved breast at about half of the institutes. On the other hand, in the cases of SLN with macrometastases, it was extended to axillary and/or supraclavicular lesions beyond the conserved breast at about 70 % of the institutes. Conclusions: Japanese breast physicians were conservative with respect to the omission of ALND in SLN-positive breast cancer, especially in the cases of SLN with macrometastases.

Original languageEnglish
Pages (from-to)427-432
Number of pages6
JournalBreast Cancer
Volume24
Issue number3
DOIs
Publication statusPublished - May 1 2017

Keywords

  • Axillary lymph node dissection
  • Breast-conserving surgery
  • Micrometastases
  • Regional node irradiation
  • Sentinel lymph node biopsy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Pharmacology (medical)

Fingerprint Dive into the research topics of 'Trends in axillary treatment for breast cancer patients undergoing sentinel lymph node biopsy as determined by a questionnaire from the Japanese Breast Cancer Society'. Together they form a unique fingerprint.

  • Cite this

    Imoto, S., Yamauchi, C., Komoike, Y., Tsugawa, K., Yotsumoto, D., Wada, N., Ueno, T., Oba, M. S., Shien, T., Sugae, S., Tsuda, H., & Yoneyama, K. (2017). Trends in axillary treatment for breast cancer patients undergoing sentinel lymph node biopsy as determined by a questionnaire from the Japanese Breast Cancer Society. Breast Cancer, 24(3), 427-432. https://doi.org/10.1007/s12282-016-0721-4