Trends and determinant factors in the use of cardiac resynchronization therapy devices in Japan: Analysis of the Japan cardiac device treatment registry database

Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Hiroshi Furushima, Yukio Sekiguchi, Tetsuyuki Manaka, Nobuhiro Nishii, Takeshi Ueyama, Norishige Morita, Takashi Nitta, Ken Okumura

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Abstract

Background: The choice of cardiac resynchronization therapy device, with (CRT-D) or without (CRT-P) a defibrillator, in patients with heart failure largely depends on the physician's discretion, because it has not been established which subjects benefit most from a defibrillator. Methods: We examined the annual trend of CRT device implantations between 2006 and 2014, and evaluated the factors related to the device selection (CRT-D or CRT-P) for primary prevention of sudden cardiac death in patients with heart failure by analyzing the Japan Cardiac Device Treatment Registry (JCDTR) database from January 2011 and August 2015 (CRT-D, . n=2714; CRT-P, . n=555). Results: The proportion of CRT-D implantations for primary prevention among all the CRT-D recipients was more than 70% during the study period. The number of CRT-D implantations for primary prevention reached a maximum in 2011 and decreased gradually between 2011 and 2014, whereas CRT-P implantations increased year by year until 2011 and remained unchanged in recent years. Multivariate analysis identified age (odds ratio [OR] 0.92, 95% confidence interval [CI] 0.90-0.95, . P

Original languageEnglish
JournalJournal of Arrhythmia
DOIs
Publication statusAccepted/In press - Mar 2 2016

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Keywords

  • Cardiac resynchronization therapy
  • Defibrillator
  • Heart failure
  • Primary prevention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Yokoshiki, H., Shimizu, A., Mitsuhashi, T., Furushima, H., Sekiguchi, Y., Manaka, T., Nishii, N., Ueyama, T., Morita, N., Nitta, T., & Okumura, K. (Accepted/In press). Trends and determinant factors in the use of cardiac resynchronization therapy devices in Japan: Analysis of the Japan cardiac device treatment registry database. Journal of Arrhythmia. https://doi.org/10.1016/j.joa.2016.04.002