Treatment of refractory metastatic choriocarcinoma with tandem high- dose chemotherapy supported by peripheral blood stem cell transplantation: A case report

Rika Kawanishi, Akihiro Bessho, Hiroshi Ueoka, Masahiro Tabata, Katsuji Shinagawa, Kenichi Chikamori, Haruyuki Kawai, Naokatsu Horita, Mine Harada

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Currently, 70% to 80% of patients with advanced germ cell tumors can be cured with cisplatin-based chemotherapy, followed by surgical resection of the residual tumor. The prognosis, however, is uniformly poor for patients who fail to respond to induction chemotherapy. In this report, we describe a patient with retroperitoneal choriocarcinoma and multiple lung metastases, who was refractory to cisplatin-based chemotherapy, but who achieved a durable marker-negative partial response after 2 cycles of high-dose chemotherapy, supported by autologous, peripheral blood stem cell transplantation. The patient is now alive and well, without recurrence, more than 24 months after this therapy.

Original languageEnglish
Pages (from-to)261-264
Number of pages4
JournalInternational Journal of Clinical Oncology
Volume3
Issue number4
DOIs
Publication statusPublished - Oct 13 1998

Keywords

  • Advanced choriocarcinoma
  • High-dose chemotherapy
  • Peripheral blood stem cell transplantation

ASJC Scopus subject areas

  • Surgery
  • Hematology
  • Oncology

Fingerprint Dive into the research topics of 'Treatment of refractory metastatic choriocarcinoma with tandem high- dose chemotherapy supported by peripheral blood stem cell transplantation: A case report'. Together they form a unique fingerprint.

  • Cite this