Treated natural history of superficial bladder cancer

Seiichiro Ozono, Shiro Hinotsu, Shoichi Tabata, Kenji Takashima, Kiyohide Fujimoto, Eigoro Okajima, Yoshihiko Hirao, Yasuo Ohashi, Hideyuki Akaza, Shoji Fukushima, Shoji Samma, Yoshiteru Kaneko, Masashi Yamamoto, Osamu Natsume, Kojiro Yoshida, Yoshihiro Tani, Hideo Aoyama, Shuji Watanabe, Shigehiro Tsujimoto, Kenichi TsumataniHisashi Matsuki, Shoki Kimura, Kazuya Hirao, Nobumichi Tani, Noboru Morita, Hitoshi Momose, Tsutomu Shiomi, Tadashi Hiramatsu, Yoriaki Kagebayashi, Yoshiki Hayashi, Akio Iwai, Akira Moriya, Yoshio Maruyama, Motoyoshi Yoshikawa

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: The present study was conducted to examine the natural history of superficial bladder cancer. Methods: One hundred and forty-four patients with superficial bladder cancer who had been treated with transurethral resection of bladder tumor (TURBt) alone were analyzed. Results: The non-recurrence rate was 64.8% at 36 months and 61.2% at 60 months after TURBt. When the non-recurrence rate after TURBt was analyzed by background variables, the rate differed significantly between the solitary tumor group and the multiple tumor group. The tumor recurrence hazard curves for the entire population had one high peak before 500 days and another slight peak around 1500 days after TURBt. Conclusions: These results will provide basic information useful when evaluating new regimens of intravesical instillation therapy for prophylaxis of superficial bladder cancer after our complete TURBt in the Nara Uro-Oncology Research Group.

Original languageEnglish
Pages (from-to)536-540
Number of pages5
JournalJapanese Journal of Clinical Oncology
Volume31
Issue number11
Publication statusPublished - 2001
Externally publishedYes

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Keywords

  • Natural history
  • Non-recurrence rate
  • Smoothed hazard
  • Superficial bladder cancer
  • Transurethral resection of bladder tumor

ASJC Scopus subject areas

  • Oncology

Cite this

Ozono, S., Hinotsu, S., Tabata, S., Takashima, K., Fujimoto, K., Okajima, E., Hirao, Y., Ohashi, Y., Akaza, H., Fukushima, S., Samma, S., Kaneko, Y., Yamamoto, M., Natsume, O., Yoshida, K., Tani, Y., Aoyama, H., Watanabe, S., Tsujimoto, S., ... Yoshikawa, M. (2001). Treated natural history of superficial bladder cancer. Japanese Journal of Clinical Oncology, 31(11), 536-540.