Transporter gene expression and transference of fructose in broiler chick intestine

Kensuke Shimizu, Yoshinori Komaki, Natsuki Fukano, Takashi Bungo

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


Recent studies have suggested that a high-fructose diet leads to the development of metabolic syndrome in mammals. However, relatively little information is available regarding the absorption of fructose in the chicken intestine. We therefore investigated fructose absorption and its transporters in the chicken small intestine. The gene expression of three transporters (glucose transporter protein member 2 and 5 and sodium-dependent glucose transporter protein 1) in the jejunum of fasted chicks were lower than those in chicks fed ad libitum. The everted intestinal sacs (in vitro method for investigating intestinal absorption) showed that the concentration of fructose uptake rapidly increased within 15 min after incubation, and then gradually increased until 60 min. After 15 min of incubation, fructose uptake in the ad libitum chick intestine was approximately 2-fold that in the fasted intestine and was less than half of the glucose uptake in the ad libitum chick intestine. Our results suggest that fructose is absorbed in the small intestine of chicks and that uptake is decreased by fasting treatment with decreases in the mRNA expression of related transporters.

Original languageEnglish
Pages (from-to)137-141
Number of pages5
JournalJournal of Poultry Science
Issue number2
Publication statusPublished - 2018
Externally publishedYes


  • Chick
  • Evert gut sac
  • Fructose
  • Glucose transporter protein member 2
  • Glucose transporter protein member 5
  • Sodium-dependent glucose transporter protein 1

ASJC Scopus subject areas

  • Animal Science and Zoology


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