Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks

Makoto Matsubayashi, Hiroki Yamaguchi, Takeshi Hatta, Fumiya Kawahara, Toshimitsu Hatabu, Hiroshi Iseki, Junya Yamagishi, Takashi Isobe, Isao Teramoto, Akira Kaneko, Kiyoshi Kita, Naotoshi Tsuji, Kazumi Sasai

Research output: Contribution to journalArticle

Abstract

Attenuated strains of avian Eimeria parasites, generated by the selection of precocious lines through serial passaging in chicks, have been used widely as live vaccines. Detailed morphological transitions including their life cycle depending on the passages remain poorly understood. Here, we showed early development and acceleration of transitions in morphological forms of the asexual schizonts of E. tenella that had been attenuated for virulence by serial passaging. Our results may be helpful in understanding parasitism, facilitating further molecular analyses such as comparative genomic or transcriptomic tests.

Original languageEnglish
Article number103993
JournalInfection, Genetics and Evolution
Volume75
DOIs
Publication statusPublished - Nov 1 2019

Fingerprint

Eimeria tenella
Schizonts
Eimeria
schizonts
vaccine
live vaccines
virulence
Life Cycle Stages
transcriptomics
parasitism
Virulence
early development
life cycle (organisms)
genomics
parasite
Parasites
Vaccines
life cycle
chicks
parasites

Keywords

  • Attenuation
  • Eimeria tenella
  • Schizont
  • Virulence

ASJC Scopus subject areas

  • Microbiology
  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics
  • Microbiology (medical)
  • Infectious Diseases

Cite this

Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks. / Matsubayashi, Makoto; Yamaguchi, Hiroki; Hatta, Takeshi; Kawahara, Fumiya; Hatabu, Toshimitsu; Iseki, Hiroshi; Yamagishi, Junya; Isobe, Takashi; Teramoto, Isao; Kaneko, Akira; Kita, Kiyoshi; Tsuji, Naotoshi; Sasai, Kazumi.

In: Infection, Genetics and Evolution, Vol. 75, 103993, 01.11.2019.

Research output: Contribution to journalArticle

Matsubayashi, M, Yamaguchi, H, Hatta, T, Kawahara, F, Hatabu, T, Iseki, H, Yamagishi, J, Isobe, T, Teramoto, I, Kaneko, A, Kita, K, Tsuji, N & Sasai, K 2019, 'Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks', Infection, Genetics and Evolution, vol. 75, 103993. https://doi.org/10.1016/j.meegid.2019.103993
Matsubayashi, Makoto ; Yamaguchi, Hiroki ; Hatta, Takeshi ; Kawahara, Fumiya ; Hatabu, Toshimitsu ; Iseki, Hiroshi ; Yamagishi, Junya ; Isobe, Takashi ; Teramoto, Isao ; Kaneko, Akira ; Kita, Kiyoshi ; Tsuji, Naotoshi ; Sasai, Kazumi. / Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks. In: Infection, Genetics and Evolution. 2019 ; Vol. 75.
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