Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: Value of diffusion-weighted imaging

Ritsuyo Kobata, Hirokazu Tsukahara, Akio Nakai, Akihiko Tanizawa, Yoshiyuki Ishimori, Yasutaka Kawamura, Hiroshi Ushijima, Mitsufumi Mayumi

Research output: Contribution to journalArticle

73 Citations (Scopus)


The authors report serial brain MR findings from a 2-year-old girl with rotavirus encephalopathy. The lesion in the splenium of the corpus callosum showed restricted proton diffusion, suggesting local cytotoxic edema. Diffusion-weighted images demonstrated the lesion more conspicuously than other techniques, such as fluid-attenuated inversion-recovery and T1- and T2-weighted images. The findings were reversible on follow-up MRI obtained 4 days later. Diffusion-weighted MRI is a potentially useful method for detecting early changes of rotavirus encephalopathy, although the mechanism of the restricted diffusion is not clearly identified.

Original languageEnglish
Pages (from-to)825-828
Number of pages4
JournalJournal of Computer Assisted Tomography
Issue number5
Publication statusPublished - Sep 2002
Externally publishedYes



  • Brain MR
  • Diffusion-weighted image
  • Rotavirus encephalopathy
  • Splenial lesion

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this