Transcatheter closure of atrial septal defects with the Amplatzer septal occluder: A Japanese clinical trial

Shinichi Oho, Akira Ishizawa, Teiji Akagi, HIdemi Dodo, Hirohisa Kato

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21 Citations (Scopus)


This study reports the results of a Japanese clinical trial of transcatheter closure of atrial septal defects (ASD) using the Amplatzer septal occluder (ASO). Thirty-five patients with secundum ASD underwent transcatheter closure using the ASO at a median age of 12,9 years (range, 3,2-29.2 years) and a median weight of 39.2kg (range, 11.6-65.1 kg). The ASO was successfully implanted in 34 patients. The mean ASD diameter of the 34 patients measured by transesophageal echocardiography was 11.7±4.2mm (range, 5.0-20.8mm) and the mean balloon stretched diameter was 16.8±4.2mm (range, 9-25mm). The mean ASO size was 16.9±4.3mm (range, 9-26mm). Complete closure rate at 1 day and 1 year after closure was 91% and 97%, respectively. One patient developed a transient second-degree atrioventricular block during the implantation procedure. No other complications occurred. Transcatheter closure of ASD using the ASO is effective and safe.

Original languageEnglish
Pages (from-to)791-794
Number of pages4
JournalCirculation Journal
Issue number9
Publication statusPublished - Sep 2002
Externally publishedYes



  • Amplatzer septal occluder
  • Atrial septal defect
  • Transcatheter closure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology

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