Transcatheter closure of atrial septal defect in a geriatric population

Koji Nakagawa, Teiji Akagi, Manabu Taniguchi, Yasufumi Kijima, Keiji Goto, Kengo F. Kusano, Hiroshi Itoh, Shunji Sano

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objectives: To evaluate the efficacy and safety of transcatheter closure of atrial septal defects (ASD) in patients over 70 years of age. Background: Transcatheter closure of ASD is an established procedure in children and young adults, but the benefits of this procedure in geriatric patients are still unclear. Methods: Between 2005 and 2010, 430 patients with ASD underwent transcatheter closure in our hospital. Among those patients, 30 consecutive patients older than 70 years of age were prospectively evaluated. Results: Mean age at procedure was 75.8 ± 3.8 years (range: 70-85 years). Mean Qp/Qs was 2.4 ± 0.7 and mean ASD diameter was 20.3 ± 6.4 mm. Nine patients (30%) had a history of hospitalization due to heart failure. ASD closure was successfully performed in 28 patients (93%) without significant complications. During the follow-up period (mean period of 19.1 ± 11.3 months), New York Heart Association (NYHA) functional class was significantly improved in 20 patients (74%). Significant improvements of plasma BNP level, resting heart rate, and systolic pulmonary artery pressure were also observed. Improvement of tricuspid regurgitation was observed in 11 of 17 patients with moderate or severe regurgitation during the follow-up period. Conversely, worsening of mitral regurgitation was observed in 10 of the 27 patients. Conclusion: Transcatheter closure of ASD in geriatric patients can be performed safely. This procedure contributes to significant improvement of symptoms and positive cardiac remodeling. Long-term follow-up is mandatory, especially for patients with mitral regurgitation.

Original languageEnglish
Pages (from-to)84-90
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Volume80
Issue number1
DOIs
Publication statusPublished - Jul 1 2012

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Atrial Heart Septal Defects
Geriatrics
Population
Mitral Valve Insufficiency
Tricuspid Valve Insufficiency
Pulmonary Artery
Young Adult
Hospitalization
Heart Failure
Heart Rate

Keywords

  • atrial septal defect
  • elderly
  • transcatheter closure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Transcatheter closure of atrial septal defect in a geriatric population. / Nakagawa, Koji; Akagi, Teiji; Taniguchi, Manabu; Kijima, Yasufumi; Goto, Keiji; Kusano, Kengo F.; Itoh, Hiroshi; Sano, Shunji.

In: Catheterization and Cardiovascular Interventions, Vol. 80, No. 1, 01.07.2012, p. 84-90.

Research output: Contribution to journalArticle

Nakagawa, Koji ; Akagi, Teiji ; Taniguchi, Manabu ; Kijima, Yasufumi ; Goto, Keiji ; Kusano, Kengo F. ; Itoh, Hiroshi ; Sano, Shunji. / Transcatheter closure of atrial septal defect in a geriatric population. In: Catheterization and Cardiovascular Interventions. 2012 ; Vol. 80, No. 1. pp. 84-90.
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