Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin

Y. Takeda, Keinosuke Okamoto, T. Miwatani

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by dethylaminoethyl-cellulose column chromatography and was not lethal for mice.

Original languageEnglish
Pages (from-to)546-548
Number of pages3
JournalInfection and Immunity
Volume18
Issue number2
Publication statusPublished - 1977
Externally publishedYes

Fingerprint

Shigella dysenteriae
Neurotoxins
Cricetulus
Cellulose
Chromatography
Ovary
Durapatite
Gels

ASJC Scopus subject areas

  • Immunology

Cite this

@article{40fd2284f77a45aaa2eee90ac93ec9c7,
title = "Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin",
abstract = "A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by dethylaminoethyl-cellulose column chromatography and was not lethal for mice.",
author = "Y. Takeda and Keinosuke Okamoto and T. Miwatani",
year = "1977",
language = "English",
volume = "18",
pages = "546--548",
journal = "Infection and Immunity",
issn = "0019-9567",
publisher = "American Society for Microbiology",
number = "2",

}

TY - JOUR

T1 - Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin

AU - Takeda, Y.

AU - Okamoto, Keinosuke

AU - Miwatani, T.

PY - 1977

Y1 - 1977

N2 - A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by dethylaminoethyl-cellulose column chromatography and was not lethal for mice.

AB - A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by dethylaminoethyl-cellulose column chromatography and was not lethal for mice.

UR - http://www.scopus.com/inward/record.url?scp=0017761641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017761641&partnerID=8YFLogxK

M3 - Article

C2 - 336549

AN - SCOPUS:0017761641

VL - 18

SP - 546

EP - 548

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 2

ER -