Toxin from the culture filtrate of Shigella dysenteriae that causes morphological changes in Chinese hamster ovary cells and is distinct from the neurotoxin

Y. Takeda, K. Okamoto, T. Miwatani

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

A toxin that causes morphological changes in Chinese hamster ovary cells was isolated from a culture filtrate of Shigella dysenteriae 1. It was partially purified by successive column chromatography on diethylaminoethyl-cellulose, Bio-Gel A-5m, and hydroxylapatite. The toxin was separated from neurotoxin by dethylaminoethyl-cellulose column chromatography and was not lethal for mice.

Original languageEnglish
Pages (from-to)546-548
Number of pages3
JournalInfection and Immunity
Volume18
Issue number2
DOIs
Publication statusPublished - 1977
Externally publishedYes

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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