Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide

Izumi Mori, Carlos R. Arias-Barreiro, Apostolos Koutsaftis, Atsushi Ogo, Tomonori Kawano, Kazuharu Yoshizuka, Salmaan H. Inayat-Hussain, Isao Aoyama

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

The aquatic ecotoxicity of chemicals involved in the manufacturing process of thin film transistor liquid crystal displays was assessed with a battery of four selected acute toxicity bioassays. We focused on tetramethylammonium hydroxide (TMAH, CAS No. 75-59-2), a widely utilized etchant. The toxicity of TMAH was low when tested in the 72h-algal growth inhibition test (Pseudokirchneriellia subcapitata, EC50=360mgL-1) and the Microtox® test (Vibrio fischeri, IC50=6.4gL-1). In contrast, the 24h-microcrustacean immobilization and the 96h-fish mortality tests showed relatively higher toxicity (Daphnia magna, EC50=32mgL-1 and Oryzias latipes, LC50=154mgL-1). Isobologram and mixture toxicity index analyses revealed apparent synergism of the mixture of TMAH and potassium iodide when examined with the D. magna immobilization test. The synergistic action was unique to iodide over other halide salts i.e. fluoride, chloride and bromide. Quaternary ammonium ions with longer alkyl chains such as tetraethylammonium and tetrabutylammonium were more toxic than TMAH in the D. magna immobilization test.

Original languageEnglish
Pages (from-to)299-304
Number of pages6
JournalChemosphere
Volume120
DOIs
Publication statusPublished - Feb 1 2015

Fingerprint

Potassium iodide
Aquatic organisms
Potassium Iodide
Aquatic Organisms
iodide
aquatic organism
Immobilization
hydroxide
Toxicity
potassium
toxicity
immobilization
Aliivibrio fischeri
Oryzias
Daphnia
Liquid Crystals
Tetraethylammonium
Poisons
Iodides
Bromides

Keywords

  • Aquatic toxicity
  • D. magna
  • Potassium iodide
  • Semiconductor wastewater
  • Synergism
  • Tetramethylammonium hydroxide

ASJC Scopus subject areas

  • Environmental Chemistry
  • Chemistry(all)
  • Medicine(all)

Cite this

Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide. / Mori, Izumi; Arias-Barreiro, Carlos R.; Koutsaftis, Apostolos; Ogo, Atsushi; Kawano, Tomonori; Yoshizuka, Kazuharu; Inayat-Hussain, Salmaan H.; Aoyama, Isao.

In: Chemosphere, Vol. 120, 01.02.2015, p. 299-304.

Research output: Contribution to journalArticle

Mori, I, Arias-Barreiro, CR, Koutsaftis, A, Ogo, A, Kawano, T, Yoshizuka, K, Inayat-Hussain, SH & Aoyama, I 2015, 'Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide', Chemosphere, vol. 120, pp. 299-304. https://doi.org/10.1016/j.chemosphere.2014.07.011
Mori, Izumi ; Arias-Barreiro, Carlos R. ; Koutsaftis, Apostolos ; Ogo, Atsushi ; Kawano, Tomonori ; Yoshizuka, Kazuharu ; Inayat-Hussain, Salmaan H. ; Aoyama, Isao. / Toxicity of tetramethylammonium hydroxide to aquatic organisms and its synergistic action with potassium iodide. In: Chemosphere. 2015 ; Vol. 120. pp. 299-304.
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