Toward the second generation synthesis of aplyronine A: Stereocontrolled assembly of the C1-C19 segment by using an asymmetric Nozaki-Hiyama-Kishi coupling

Kenichi Kobayashi, Yusuke Fujii, Ichiro Hayakawa, Hideo Kigoshi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

An efficient synthesis of the C1-C19 segment of aplyronine A is described. Stereoselective construction of the C14-C15 (E)-trisubstituted double bond and the C13 stereocenter was achieved by using an asymmetric Nozaki-Hiyama-Kishi coupling.(Figure Presented)

Original languageEnglish
Pages (from-to)900-903
Number of pages4
JournalOrganic Letters
Volume13
Issue number5
DOIs
Publication statusPublished - Mar 4 2011
Externally publishedYes

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assembly
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ASJC Scopus subject areas

  • Organic Chemistry
  • Physical and Theoretical Chemistry
  • Biochemistry

Cite this

Toward the second generation synthesis of aplyronine A : Stereocontrolled assembly of the C1-C19 segment by using an asymmetric Nozaki-Hiyama-Kishi coupling. / Kobayashi, Kenichi; Fujii, Yusuke; Hayakawa, Ichiro; Kigoshi, Hideo.

In: Organic Letters, Vol. 13, No. 5, 04.03.2011, p. 900-903.

Research output: Contribution to journalArticle

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