Abstract
Stereoselective and parallel total syntheses of two possible diastereomers of (+)-sarcophytonolide C have been accomplished. Macrolactonization and transannular ring-closing metathesis (RCM) were the key transformations. Detailed comparisons of their 1H and 13C NMR data and specific rotation with those of the natural product allowed the absolute configuration of (+)-sarcophytonolide C to be determined.
| Original language | English |
|---|---|
| Pages (from-to) | 1108-1111 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 15 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - 2013 |
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ASJC Scopus subject areas
- Organic Chemistry
- Physical and Theoretical Chemistry
- Biochemistry
Cite this
Total synthesis of two possible diastereomers of (+)-sarcophytonolide C and its structural elucidation. / Takamura, Hiroyoshi; Iwamoto, Kohei; Nakao, Eiji; Kadota, Isao.
In: Organic Letters, Vol. 15, No. 5, 2013, p. 1108-1111.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Total synthesis of two possible diastereomers of (+)-sarcophytonolide C and its structural elucidation
AU - Takamura, Hiroyoshi
AU - Iwamoto, Kohei
AU - Nakao, Eiji
AU - Kadota, Isao
PY - 2013
Y1 - 2013
N2 - Stereoselective and parallel total syntheses of two possible diastereomers of (+)-sarcophytonolide C have been accomplished. Macrolactonization and transannular ring-closing metathesis (RCM) were the key transformations. Detailed comparisons of their 1H and 13C NMR data and specific rotation with those of the natural product allowed the absolute configuration of (+)-sarcophytonolide C to be determined.
AB - Stereoselective and parallel total syntheses of two possible diastereomers of (+)-sarcophytonolide C have been accomplished. Macrolactonization and transannular ring-closing metathesis (RCM) were the key transformations. Detailed comparisons of their 1H and 13C NMR data and specific rotation with those of the natural product allowed the absolute configuration of (+)-sarcophytonolide C to be determined.
UR - http://www.scopus.com/inward/record.url?scp=84874591046&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84874591046&partnerID=8YFLogxK
U2 - 10.1021/ol400157s
DO - 10.1021/ol400157s
M3 - Article
VL - 15
SP - 1108
EP - 1111
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 5
ER -