Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach

Takuma Kamon; Yayoi Irifune; Tetsuaki Tanaka; Takehiko Yoshimitsu

doi:10.1021/ol200772f

Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach

Takuma Kamon, Yayoi Irifune, Tetsuaki Tanaka, Takehiko Yoshimitsu

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

A novel photochemical C-H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.

Original language	English
Pages (from-to)	2674-2677
Number of pages	4
Journal	Organic Letters
Volume	13
Issue number	10
DOIs	https://doi.org/10.1021/ol200772f
Publication status	Published - May 20 2011
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ol200772f

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title = "Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach",

abstract = "A novel photochemical C-H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.",

author = "Takuma Kamon and Yayoi Irifune and Tetsuaki Tanaka and Takehiko Yoshimitsu",

year = "2011",

month = may,

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doi = "10.1021/ol200772f",

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T1 - Total synthesis of (±)-kainic acid

T2 - A photochemical C-H carbamoylation approach

AU - Kamon, Takuma

AU - Irifune, Yayoi

AU - Tanaka, Tetsuaki

AU - Yoshimitsu, Takehiko

PY - 2011/5/20

Y1 - 2011/5/20

N2 - A novel photochemical C-H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.

AB - A novel photochemical C-H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.

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JO - Organic Letters

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Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach

Abstract

ASJC Scopus subject areas

UN SDGs

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