Total synthesis of (±)-kainic acid: A photochemical C-H carbamoylation approach

Takuma Kamon, Yayoi Irifune, Tetsuaki Tanaka, Takehiko Yoshimitsu

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

A novel photochemical C-H carbamoylation of an octahydroisoindole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (±)-kainic acid, a bioactive marine alkaloid, has been accomplished.

Original languageEnglish
Pages (from-to)2674-2677
Number of pages4
JournalOrganic Letters
Volume13
Issue number10
DOIs
Publication statusPublished - May 20 2011
Externally publishedYes

Fingerprint

alkaloids
Kainic Acid
activity (biology)
Alkaloids
Proline
Derivatives
acids
synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Total synthesis of (±)-kainic acid : A photochemical C-H carbamoylation approach. / Kamon, Takuma; Irifune, Yayoi; Tanaka, Tetsuaki; Yoshimitsu, Takehiko.

In: Organic Letters, Vol. 13, No. 10, 20.05.2011, p. 2674-2677.

Research output: Contribution to journalArticle

Kamon, Takuma ; Irifune, Yayoi ; Tanaka, Tetsuaki ; Yoshimitsu, Takehiko. / Total synthesis of (±)-kainic acid : A photochemical C-H carbamoylation approach. In: Organic Letters. 2011 ; Vol. 13, No. 10. pp. 2674-2677.
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