Total synthesis of gambierol

Isao Kadota, Hiroyoshi Takamura, Kumi Sato, Akio Ohno, Kumiko Matsuda, Yoshinori Yamamoto

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

The convergent total synthesis of gambierol (1) is described. The octacyclic ether framework of 1 was constructed via the intramolecular allylation of α-chloroacetoxy ether followed by ring-closing metathesis. A modified Stille coupling was successfully applied to the synthesis of the triene side chain.

Original languageEnglish
Pages (from-to)46-47
Number of pages2
JournalJournal of the American Chemical Society
Volume125
Issue number1
DOIs
Publication statusPublished - Jan 8 2003
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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