Total synthesis of carbazole-1,4-quinone alkaloid koeniginequinones a and B based on a one-pot cyclocarbonylation procedure from 2-alkenyl-3-iodoindole

Takashi Nishiyama, Nanase Satsuki, Satoshi Hibino, Mami Fujii, Takumi Abe, Minoru Ishikura, Tominari Choshi

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Total syntheses of koeniginequinones A and B, isolated from Murraya koenigii, were newly achieved by constructing of carbazole-1,4-quinone using a one-pot Pd-catalyzed cyclocarbonylation method with 2-(but-2-en-1-yl)-3-iodoindoles derived from known methyl 6-methoxyindole-2-carboxylate and methyl 5,6-dimethoxyindole-2-carboxylate, followed by desilylation, and an oxidation sequence.

Original languageEnglish
Pages (from-to)84-100
Number of pages17
JournalHeterocycles
Volume93
Issue number1
DOIs
Publication statusPublished - 2016
Externally publishedYes

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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