Total Synthesis of Biselyngbyaside

Eisuke Sato, Miho Sato, Yurika Tanabe, Naoya Nakajima, Akifumi Ohkubo, Kiyotake Suenaga

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The first total synthesis of biselyngbyaside, an 18-membered macrolide glycoside, was achieved. The glycoside bond was introduced using the Schmidt method before construction of the 18-membered ring due to the instability of the conjugated diene and the β-hydroxy ester moiety. The macrolactone ring was constructed using the Mitsunobu reaction followed by intramolecular the Stille coupling reaction.

Original languageEnglish
Pages (from-to)6770-6777
Number of pages8
JournalJournal of Organic Chemistry
Volume82
Issue number13
DOIs
Publication statusPublished - Jul 7 2017
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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