Abstract
A covenient and versatile synthesis of benzo[c]phenanthridine alkaloids, chelerythrine (1) and 12-methoxydihydrochelerythrine (5), was accomplished via an internal aryl-aryl coupling reaction of haloamides 8 and 9 by a palladium-assisted cyclization reaction.
Original language | English |
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Pages (from-to) | 444-450 |
Number of pages | 7 |
Journal | Synthesis |
Issue number | 3 |
DOIs | |
Publication status | Published - 2001 |
Keywords
- Alkaloids
- Haloamides
- Heck-type reaction
- Internal aryl-aryl coupling
- Palladium
- Ring closure
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry