Total synthesis of auripyrones A and B and determination of the absolute configuration of auripyrone B

Ichiro Hayakawa, Takuma Takemura, Emi Fukasawa, Yuta Ebihara, Natsuki Sato, Takayasu Nakamura, Kiyotake Suenaga, Hideo Kigoshi

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

(Figure Presented) The winner takes it aldol: The total synthesis of auripyrones A and B was achieved using a diastereoselective aldol-type reaction with 2, 6-diethyl-3, 5-dimethyl-4-pyrone as a key step. The stereostructure and absolute configura-tion of auripyrone B has also been determined.

Original languageEnglish
Pages (from-to)2401-2405
Number of pages5
JournalAngewandte Chemie - International Edition
Volume49
Issue number13
Publication statusPublished - Mar 22 2010
Externally publishedYes

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Keywords

  • Aldol reactions
  • Auripyrones
  • Diastereoselectivity
  • Natural products
  • Total synthesis

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Medicine(all)

Cite this

Hayakawa, I., Takemura, T., Fukasawa, E., Ebihara, Y., Sato, N., Nakamura, T., Suenaga, K., & Kigoshi, H. (2010). Total synthesis of auripyrones A and B and determination of the absolute configuration of auripyrone B. Angewandte Chemie - International Edition, 49(13), 2401-2405.