Abstract
Asymmetric synthesis of amphidinolactone A, a cytotoxic macrolide from the cultured dinoflagellate Amphidinium sp., has been accomplished. Absolute configuration of amphidinolactone A was concluded to be 1 from comparison of the NMR data and [α]D values of synthetic and natural amphidinolactone A.
Original language | English |
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Pages (from-to) | 1475-1477 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 50 |
Issue number | 13 |
DOIs | |
Publication status | Published - Apr 1 2009 |
Externally published | Yes |
Keywords
- Amphidinium sp.
- Amphidinolactone A
- Macrolide
- Stereochemistry
- Synthesis
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry