Tooth pulp primary neurons: Cell size analysis, central connection, and carbonic anhydrase activity

Tomosada Sugimoto, Motohide Takemura

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Cell bodies and central terminals of trigeminal primary afferent neurons innervating the mandibular molar and incisor tooth pulps were labeled by injecting various neuroanatomical tracers into these tooth pulps. The cell bodies of major constituents of primary neurons innervating the tooth pulp, cornea, and cutaneous branch of the mylohyoid nerve were large (≥500 μm2, 65%), medium (300-400 μm2, 35%), and small (100-200 μm2, 34%), respectively. Those innervating the tooth pulp (tooth pulp cells) had the Nissl pattern characteristic of large light cells of the A type, while those innervating the cornea were small dark cells of the B type. Thirty percent of the tooth pulp cells exhibited histochemically demonstrable carbonic anhydrase activity. The transganglionic transport of HRP-WGA indicated marked concentration of central terminals of the tooth pulp primaries in the rostral subdivisions of the brain stem sensory trigeminal nuclear complex. In contrast, central terminals of the corneal primaries were concentrated in the medullary dorsal horn.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalBrain Research Bulletin
Volume30
Issue number3-4
DOIs
Publication statusPublished - 1993

Keywords

  • Carbonic anhydrase
  • Cell size analysis
  • Primary neuron
  • Tooth pulp

ASJC Scopus subject areas

  • Neuroscience(all)

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