Thyroid cancer detection by ultrasound among residents ages 18 years and younger in Fukushima, Japan: 2011 to 2014

Toshihide Tsuda, Akiko Tokinobu, Eiji Yamamoto, Etsuji Suzuki

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Abstract

Background: after the great east Japan earthquake and tsunami in March 2011, radioactive elements were released from the Fukushima Daiichi nuclear Power Plant. Based on prior knowledge, concern emerged about whether an increased incidence of thyroid cancer among exposed residents would occur as a result. Methods: after the release, Fukushima Prefecture performed ultrasound thyroid screening on all residents ages ¡Ü18 years. the first round of screening included 298,577 examinees, and a second round began in april 2014. We analyzed the prefecture results from the first and second round up to December 31, 2014, in comparison with the Japanese annual incidence and the incidence within a reference area in Fukushima Prefecture. Results: the highest incidence rate ratio, using a latency period of 4 years, was observed in the central middle district of the prefecture compared with the Japanese annual incidence (incidence rate ratio = 50; 95% confidence interval [ci] = 25, 90). the prevalence of thyroid cancer was 605 per million examinees (95% ci = 302, 1,082) and the prevalence odds ratio compared with the reference district in Fukushima Prefecture was 2.6 (95% ci = 0.99, 7.0). in the second screening round, even under the assumption that the rest of examinees were disease free, an incidence rate ratio of 12 has already been observed (95% ci = 5.1, 23). Conclusions: an excess of thyroid cancer has been detected by ultrasound among children and adolescents in Fukushima Prefecture within 4 years of the release, and is unlikely to be explained by a screening surge.

Original languageEnglish
Pages (from-to)316-322
Number of pages7
JournalEpidemiology
Volume27
Issue number3
DOIs
Publication statusPublished - 2016

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Thyroid Neoplasms
Japan
Incidence
Confidence Intervals
Radioactive Elements
Tsunamis
Nuclear Power Plants
Earthquakes
Thyroid Gland
Odds Ratio

ASJC Scopus subject areas

  • Epidemiology

Cite this

Thyroid cancer detection by ultrasound among residents ages 18 years and younger in Fukushima, Japan : 2011 to 2014. / Tsuda, Toshihide; Tokinobu, Akiko; Yamamoto, Eiji; Suzuki, Etsuji.

In: Epidemiology, Vol. 27, No. 3, 2016, p. 316-322.

Research output: Contribution to journalArticle

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