Thrombotic thrombocytopenic purpura and myoglobinuric acute renal failure following radiation therapy in a patient with polymyositis and cervical cancer.

Hirofumi Makino, Y. Nagake, K. Moriwaki, S. Hirakawa, T. Katayama, H. Yanai, Hiroyuki Yanai, T. Akagi, Z. Ota

Research output: Contribution to journalArticle

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Abstract

A 73-year-old woman was admitted to receive radiation treatment for uterine cervical cancer, however a complex series of events ensued, leading to death. She developed an acute exacerbation of polymyositis complicated by thrombotic thrombocytopenic purpura, rhabdomyolysis and acute renal failure. Radiation therapy may have produced an immune disturbance leading to the acute exacerbation of polymyositis. Auto-immune-mediated endothelial damage might have triggered a series of events leading to thrombotic thrombocytopenic purpura. Rhabdomyolysis seemed to be the main cause of acute renal failure.

Original languageEnglish
Pages (from-to)24-27
Number of pages4
JournalInternal Medicine
Volume34
Issue number1
Publication statusPublished - Jan 1995

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Thrombotic Thrombocytopenic Purpura
Polymyositis
Rhabdomyolysis
Acute Kidney Injury
Uterine Cervical Neoplasms
Radiotherapy
Radiation
Therapeutics

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Thrombotic thrombocytopenic purpura and myoglobinuric acute renal failure following radiation therapy in a patient with polymyositis and cervical cancer. / Makino, Hirofumi; Nagake, Y.; Moriwaki, K.; Hirakawa, S.; Katayama, T.; Yanai, H.; Yanai, Hiroyuki; Akagi, T.; Ota, Z.

In: Internal Medicine, Vol. 34, No. 1, 01.1995, p. 24-27.

Research output: Contribution to journalArticle

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