Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata

Q. W. Shi, T. Oritani, Hiromasa Kiyota

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidata. Their structures were established as 5α,13α-diacetoxy-taxa-4(20),11-diene-9α,10β-diol (1), 7β,13α-diacetoxy-5α-cinnamyloxy-2(3→20)-abeo-taxa-4(20),11 -diene-2α,10β-diol (2), and 2α,10β,13α-triacetoxy-taxa-4(20),11-diene-5α,7β,9 α-triol (3)respectively on the basis of 1D and 2D NMR data.

Original languageEnglish
Pages (from-to)55-62
Number of pages8
JournalNatural Product Letters
Volume15
Issue number1
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Taxus cuspidata
Taxus
Taxoids
glycols
Diterpenes
Nuclear magnetic resonance
taxanes
diterpenoids
leaves
2,10,13-triacetoxy-taxa-4(20),11-diene-5,7,9-triol
5,13 -diacetoxy-taxa-4(20),11-diene-9,10-diol
taxane

Keywords

  • Leaves
  • Taxaceae
  • Taxoids
  • Taxus cuspidata

ASJC Scopus subject areas

  • Molecular Medicine

Cite this

Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata. / Shi, Q. W.; Oritani, T.; Kiyota, Hiromasa.

In: Natural Product Letters, Vol. 15, No. 1, 2001, p. 55-62.

Research output: Contribution to journalArticle

@article{dda15b06ff7c479d8ac3a008cc738b1b,
title = "Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata",
abstract = "Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidata. Their structures were established as 5α,13α-diacetoxy-taxa-4(20),11-diene-9α,10β-diol (1), 7β,13α-diacetoxy-5α-cinnamyloxy-2(3→20)-abeo-taxa-4(20),11 -diene-2α,10β-diol (2), and 2α,10β,13α-triacetoxy-taxa-4(20),11-diene-5α,7β,9 α-triol (3)respectively on the basis of 1D and 2D NMR data.",
keywords = "Leaves, Taxaceae, Taxoids, Taxus cuspidata",
author = "Shi, {Q. W.} and T. Oritani and Hiromasa Kiyota",
year = "2001",
language = "English",
volume = "15",
pages = "55--62",
journal = "Natural Product Research",
issn = "1478-6419",
publisher = "Taylor and Francis Ltd.",
number = "1",

}

TY - JOUR

T1 - Three new taxoids from the leaves of the Japanese yew, Taxus cuspidata

AU - Shi, Q. W.

AU - Oritani, T.

AU - Kiyota, Hiromasa

PY - 2001

Y1 - 2001

N2 - Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidata. Their structures were established as 5α,13α-diacetoxy-taxa-4(20),11-diene-9α,10β-diol (1), 7β,13α-diacetoxy-5α-cinnamyloxy-2(3→20)-abeo-taxa-4(20),11 -diene-2α,10β-diol (2), and 2α,10β,13α-triacetoxy-taxa-4(20),11-diene-5α,7β,9 α-triol (3)respectively on the basis of 1D and 2D NMR data.

AB - Three new taxane diterpenoids were isolated from the leaves of the Japanese yew, Taxus cuspidata. Their structures were established as 5α,13α-diacetoxy-taxa-4(20),11-diene-9α,10β-diol (1), 7β,13α-diacetoxy-5α-cinnamyloxy-2(3→20)-abeo-taxa-4(20),11 -diene-2α,10β-diol (2), and 2α,10β,13α-triacetoxy-taxa-4(20),11-diene-5α,7β,9 α-triol (3)respectively on the basis of 1D and 2D NMR data.

KW - Leaves

KW - Taxaceae

KW - Taxoids

KW - Taxus cuspidata

UR - http://www.scopus.com/inward/record.url?scp=0035065793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035065793&partnerID=8YFLogxK

M3 - Article

C2 - 11547424

AN - SCOPUS:0035065793

VL - 15

SP - 55

EP - 62

JO - Natural Product Research

JF - Natural Product Research

SN - 1478-6419

IS - 1

ER -