Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano, Ayano Kotake, Hirofumi Hashima, Ichiro Hayakawa, Hatsue Hiraide, Hui Ping Zhang, Haruhisa Kizu, Kanki Komiyama, Masahiko Hayashi, George R. Pettit

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36 Citations (Scopus)

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Original languageEnglish
Pages (from-to)1147-1153
Number of pages7
JournalCollection of Czechoslovak Chemical Communications
Volume64
Issue number7
DOIs
Publication statusPublished - Jan 1 1999
Externally publishedYes

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Keywords

  • (2-phenylethyl)amine alkaloids
  • 3-hydroxyindol-2(3H)-one
  • Amathia convoluta
  • Bryozoa
  • Convolutamine F
  • Convolutamine G
  • Convolutamydine E
  • Cytostatic activity
  • Isolation
  • Marine natural products

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Kamano, Y., Kotake, A., Hashima, H., Hayakawa, I., Hiraide, H., Zhang, H. P., Kizu, H., Komiyama, K., Hayashi, M., & Pettit, G. R. (1999). Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta. Collection of Czechoslovak Chemical Communications, 64(7), 1147-1153. https://doi.org/10.1135/cccc19991147