Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta

Yoshiaki Kamano, Ayano Kotake, Hirofumi Hashima, Ichiro Hayakawa, Hatsue Hiraide, Hui Ping Zhang, Haruhisa Kizu, Kanki Komiyama, Masahiko Hayashi, George R. Pettit

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Two new (2-phenylethyl)amine alkaloids, convolutamines F and G, and a dibromohydroxy-oxindole alkaloid, convolutamydine E, have been isolated from the butan-1-ol soluble material of the Floridian marine bryozoan Amathia convoluta. Their structures were elucidated on the basis of spectroscopic data. Convolutamine F exhibited activity against KB, KB/VJ-300, and U937 cells. This compound also exhibited the inhibitory effects for cell division of fertilized sea urchin eggs.

Original languageEnglish
Pages (from-to)1147-1153
Number of pages7
JournalCollection of Czechoslovak Chemical Communications
Volume64
Issue number7
Publication statusPublished - 1999
Externally publishedYes

Fingerprint

Alkaloids
Amines
Cells
convolutamydine E
oxindole

Keywords

  • (2-phenylethyl)amine alkaloids
  • 3-hydroxyindol-2(3H)-one
  • Amathia convoluta
  • Bryozoa
  • Convolutamine F
  • Convolutamine G
  • Convolutamydine E
  • Cytostatic activity
  • Isolation
  • Marine natural products

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta. / Kamano, Yoshiaki; Kotake, Ayano; Hashima, Hirofumi; Hayakawa, Ichiro; Hiraide, Hatsue; Zhang, Hui Ping; Kizu, Haruhisa; Komiyama, Kanki; Hayashi, Masahiko; Pettit, George R.

In: Collection of Czechoslovak Chemical Communications, Vol. 64, No. 7, 1999, p. 1147-1153.

Research output: Contribution to journalArticle

Kamano, Y, Kotake, A, Hashima, H, Hayakawa, I, Hiraide, H, Zhang, HP, Kizu, H, Komiyama, K, Hayashi, M & Pettit, GR 1999, 'Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta', Collection of Czechoslovak Chemical Communications, vol. 64, no. 7, pp. 1147-1153.
Kamano, Yoshiaki ; Kotake, Ayano ; Hashima, Hirofumi ; Hayakawa, Ichiro ; Hiraide, Hatsue ; Zhang, Hui Ping ; Kizu, Haruhisa ; Komiyama, Kanki ; Hayashi, Masahiko ; Pettit, George R. / Three new alkaloids, convolutamines F and G, and convolutamydine E, from the Floridian marine bryozoan Amathia convoluta. In: Collection of Czechoslovak Chemical Communications. 1999 ; Vol. 64, No. 7. pp. 1147-1153.
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AU - Kotake, Ayano

AU - Hashima, Hirofumi

AU - Hayakawa, Ichiro

AU - Hiraide, Hatsue

AU - Zhang, Hui Ping

AU - Kizu, Haruhisa

AU - Komiyama, Kanki

AU - Hayashi, Masahiko

AU - Pettit, George R.

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