Three-component coupling based on the "cation pool" method

Seiji Suga, Tomoaki Nishida, Daisuke Yamada, Aiichiro Nagaki, Jun Ichi Yoshida

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)


Sequential one-pot three-component coupling reactions have been developed based on the "cation pool" method. An N-acyliminium ion generated by the "cation pool" method adds to an electron-rich carbon-carbon double bond, such as enamine derivatives and vinyl sulfides, to form the second "cation pool". The addition of nucleophiles such as allylsilanes, enol silyl ethers, Grignard reagents, and organoaluminum compounds led to the formation of the corresponding three-component coupling products.

Original languageEnglish
Pages (from-to)14338-14339
Number of pages2
JournalJournal of the American Chemical Society
Issue number44
Publication statusPublished - Nov 10 2004
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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