Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis

Nurliza Binti Md Nor, Tomoyuki Kusumoto, Seiji Inoue, Keiichiro Nakamura, Noriko Seki, Atsushi Hongo, Junichi Kodama, Yuji Hiramatsu

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Struma ovarii is a rare neoplasm that accounts for approximately 0.3% of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31-50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple Tl-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalActa Medica Okayama
Volume67
Issue number3
Publication statusPublished - 2013

Fingerprint

Struma Ovarii
Laparoscopy
Surgery
Tumors
Imaging techniques
Magnetic resonance
Neoplasms
Positron emission tomography
Thyroglobulin
Tomography
Ultrasonics
Magnetic Resonance Imaging
Radionuclide Imaging
Laparotomy
Cysts
Rupture
Carcinoma

Keywords

  • Laparoscopic surgery
  • MRI
  • Ovarian neoplasms
  • struma ovarii

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Nor, N. B. M., Kusumoto, T., Inoue, S., Nakamura, K., Seki, N., Hongo, A., ... Hiramatsu, Y. (2013). Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis. Acta Medica Okayama, 67(3), 191-195.

Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis. / Nor, Nurliza Binti Md; Kusumoto, Tomoyuki; Inoue, Seiji; Nakamura, Keiichiro; Seki, Noriko; Hongo, Atsushi; Kodama, Junichi; Hiramatsu, Yuji.

In: Acta Medica Okayama, Vol. 67, No. 3, 2013, p. 191-195.

Research output: Contribution to journalArticle

Nor, NBM, Kusumoto, T, Inoue, S, Nakamura, K, Seki, N, Hongo, A, Kodama, J & Hiramatsu, Y 2013, 'Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis', Acta Medica Okayama, vol. 67, no. 3, pp. 191-195.
Nor, Nurliza Binti Md ; Kusumoto, Tomoyuki ; Inoue, Seiji ; Nakamura, Keiichiro ; Seki, Noriko ; Hongo, Atsushi ; Kodama, Junichi ; Hiramatsu, Yuji. / Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis. In: Acta Medica Okayama. 2013 ; Vol. 67, No. 3. pp. 191-195.
@article{8a1e8e15ab274e0197b3d91884de40de,
title = "Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis",
abstract = "Struma ovarii is a rare neoplasm that accounts for approximately 0.3{\%} of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31-50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple Tl-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.",
keywords = "Laparoscopic surgery, MRI, Ovarian neoplasms, struma ovarii",
author = "Nor, {Nurliza Binti Md} and Tomoyuki Kusumoto and Seiji Inoue and Keiichiro Nakamura and Noriko Seki and Atsushi Hongo and Junichi Kodama and Yuji Hiramatsu",
year = "2013",
language = "English",
volume = "67",
pages = "191--195",
journal = "Acta Medica Okayama",
issn = "0386-300X",
publisher = "Okayama University",
number = "3",

}

TY - JOUR

T1 - Three Cases of Struma Ovarii Underwent Laparoscopic Surgery with Definite Preoperative Diagnosis

AU - Nor, Nurliza Binti Md

AU - Kusumoto, Tomoyuki

AU - Inoue, Seiji

AU - Nakamura, Keiichiro

AU - Seki, Noriko

AU - Hongo, Atsushi

AU - Kodama, Junichi

AU - Hiramatsu, Yuji

PY - 2013

Y1 - 2013

N2 - Struma ovarii is a rare neoplasm that accounts for approximately 0.3% of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31-50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple Tl-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.

AB - Struma ovarii is a rare neoplasm that accounts for approximately 0.3% of ovarian tumors. Due to its ultrasound morphology, which is quite similar to that of malignant ovarian carcinoma, most struma ovarii cases are open operated with laparotomy rather than laparoscopy. We present 3 cases of struma ovarii, which were diagnosed preoperatively by imaging studies and removed by laparoscopic surgery. All patients were premenopausal women between ages 31-50. The magnetic resonance imaging (MRI) findings were complex masses composed of multiple cysts and solid components with T2-hypointense regions as well as multiple Tl-hyperintense cystic areas, findings that are typical for struma ovarii. A combination of plain computed tomography (CT), positron emission tomography (PET)-CT, and scintigraphy was useful for diagnosis. Laboratory examination revealed elevated serum thyroglobulin, which led to the diagnosis of struma ovarii. Laparoscopic surgeries were performed without rupturing the tumors. Although it has been difficult to differentiate between struma ovarii and malignant tumors by conventional methods, recently MRI techniques appear make it possible to diagnose struma ovarii preoperatively from the abovementioned imaging characteristic, together with laboratory data. As for treatment, we think laparoscopy could be successful for struma ovarii, but the surgeon must be careful not to rupture the tumor intra-abdominally in order to prevent dissemination, which could lead to malignancy.

KW - Laparoscopic surgery

KW - MRI

KW - Ovarian neoplasms

KW - struma ovarii

UR - http://www.scopus.com/inward/record.url?scp=84883202040&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84883202040&partnerID=8YFLogxK

M3 - Article

VL - 67

SP - 191

EP - 195

JO - Acta Medica Okayama

JF - Acta Medica Okayama

SN - 0386-300X

IS - 3

ER -