Thiol modification by bioactivated polyphenols and its potential role in skin Inflammation

Yoshimasa Nakamura, Takeshi Ishii, Naomi Abe, Yoshiyuki Murata

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

In the present study, we evaluated the modifying behavior of simple phenolic compounds on the sulfhydryl groups of glutathione and proteins. The catechol-type polyphenols, including protocatechuic acid, but neither the monophenols nor O-methylated catechol, can modify the sulfhydryl groups in a phenol oxidase-dependent manner. The possible involvement of polyphenol bioactivation in the enhancement of skin inflammation was also suggested.

Original languageEnglish
Pages (from-to)1067-1070
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume78
Issue number6
DOIs
Publication statusPublished - 2014

Fingerprint

Polyphenols
Sulfhydryl Compounds
Skin
Inflammation
Monophenol Monooxygenase
Glutathione
Proteins
catechol
protocatechuic acid

Keywords

  • Glutathione
  • Polyphenol
  • Protein thiols
  • Skin inflammation
  • Tyrosinase

ASJC Scopus subject areas

  • Biotechnology
  • Biochemistry
  • Molecular Biology
  • Applied Microbiology and Biotechnology
  • Analytical Chemistry
  • Organic Chemistry
  • Medicine(all)

Cite this

Thiol modification by bioactivated polyphenols and its potential role in skin Inflammation. / Nakamura, Yoshimasa; Ishii, Takeshi; Abe, Naomi; Murata, Yoshiyuki.

In: Bioscience, Biotechnology and Biochemistry, Vol. 78, No. 6, 2014, p. 1067-1070.

Research output: Contribution to journalArticle

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