Thermospermine: An evolutionarily ancient but functionally new compound in plants

Research output: Chapter in Book/Report/Conference proceedingChapter

3 Citations (Scopus)

Abstract

Themospermine is a structural isomer of spermine and is present in some bacteria and most of plants. An Arabidopsis mutant, acaulis5 (acl5), that is defective in the biosynthesis of thermospermine displays excessive proliferation of xylem vessels with dwarfed growth. Recent studies using acl5 and its suppressor mutants that recover the growth without thermospermine have revealed that thermospermine plays a key role in the negative control of the proliferation of xylem vessels through enhancing translation of specific mRNAs that contain a conserved upstream open-reading-frame (uORF) in the 50 leader region.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages51-59
Number of pages9
Volume1694
DOIs
Publication statusPublished - 2018

Publication series

NameMethods in Molecular Biology
Volume1694
ISSN (Print)1064-3745

Keywords

  • Acaulis5
  • Arabidopsis
  • mRNA translation
  • Thermospermine
  • uORF
  • Xylem

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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