The Utility of the CHA2DS2-VASC Score to Predict the Left Atrial Appendage Sludge /Thrombus in Patients with Atrial Fibrillation

Satoshi Kawada, Atsuyuki Watanabe, Tadashi Wada, Ritsuko Terasaka, Yuji Koide, Hajime Nakahama

Research output: Contribution to journalArticle


Purpose: The aim of this study was to assess what parameters predict the left atrial (LA) / LA appendage (LAA) sludge/thrombus on transesophageal echocardiography (TEE) in patients with atrial fibrillation (AF). Methods and Results: Total two-hundred and forty-eight patients (age 66 ± 12 years, BNP 150±220, PT-INR 2.2±0.9, CHADS2 1.67±1.24, CHA2DS2-VASc score 2.81 ±1.87) underwent TEE screening studies between January 2007 and December 2010 in our hospital. Almost all the cases were seen prior to electrical defibrillation. PAF/PAT was observed in 69 and 10 patients, respectively and CAF in 142. The prevalence of LA/LAA thrombi, sludge, and spontaneous echo contrast (SEC) was 11%, 7%, and 24%, respectively. Compared with the normal/spontaneous echo contrast (SEC) patients, the LA/LAA sludge/thrombus patients had a higher mean CHA2DS2-VASc score (3.2±1.82 vs. 2.6±1.83 P<0.05), larger LA volume (47±7 vs.42±8 P<0.01) and smaller LA appendage velocity (0.37 ±0.17vs. 0.51 ±0.21 P<0.05), and it was not significantly correlated with the CHADS2 score (1.9± 1.1 vs.1.6±1.2 P=0.07). Conclusion: For the clinical parameters, the CHA2DS2Vasc score was significantly related to the prevalence of LA/LAA sludge/thrombi in patients with AF.

Original languageEnglish
Pages (from-to)281
Number of pages1
JournalJournal of Arrhythmia
Issue number4
Publication statusPublished - 2011
Externally publishedYes



  • CHA2DS2Vasc
  • sludge/thrombus
  • transesophageal echocardiography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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