The usefulness of readout-segmented echo-planar imaging (RESOLVE) for bio-phantom imaging using 3-tesla clinical MRI

Yuuki Yoshimura, Masahiro Kuroda, Irfan Sugianto, Babatunde O. Bamgbose, Kanae Miyahara, Yuichi Ohmura, Akira Kurozumi, Toshi Matsushita, Seiichiro Ohno, Susumu Kanazawa, Junichi Asaumi

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Readout-segmented echo-planar imaging (RESOLVE) is a multi-shot echo-planar imaging (EPI) modality with k-space segmented in the readout direction. We investigated whether RESOLVE decreases the distortion and artifact in the phase direction and increases the signal-to-noise ratio (SNR) in phantoms image taken with 3-tesla (3T) MRI versus conventional EPI. We used a physiological saline phantom and subtraction mapping and observed that RESOLVE's SNR was higher than EPI's. Using RESOLVE, the combination of a special-purpose coil and a large-loop coil had a higher SNR compared to using only a head/neck coil. RESOLVE's image distortion was less than EPI's. We used a 120 mM polyethylene glycol phantom to examine the phase direction artifact. The range where the artifact appeared in the apparent diffusion coefficient (ADC) image was shorter with RESOLVE compared to EPI. We used RESOLVE to take images of a Jurkat cell bio-phantom: the cell-region ADC was 856×10-6mm2/sec and the surrounding physiological saline-region ADC was 2,951×10-6mm2/sec. The combination of RESOLVE and the 3T clinical MRI device reduced image distortion and improved SNR and the identification of accurate ADC values due to the phase direction artifact reduction. This combination is useful for obtaining accurate ADC values of bio-phantoms.

Original languageEnglish
Pages (from-to)53-59
Number of pages7
JournalActa medica Okayama
Issue number1
Publication statusPublished - 2018


  • 3 tesla MRI
  • Apparent diffusion coefficient
  • Bio-phantom
  • Diffusion-weighted imaging

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


Dive into the research topics of 'The usefulness of readout-segmented echo-planar imaging (RESOLVE) for bio-phantom imaging using 3-tesla clinical MRI'. Together they form a unique fingerprint.

Cite this