The structural variation in the incubation products of (-)-epigallocatechin gallate in neutral solution suggests its breakdown pathways

Tsutomu Hatano; Takayo Ohyabu; Takashi Yoshida

doi:10.3987/COM-04-10259

The structural variation in the incubation products of (-)-epigallocatechin gallate in neutral solution suggests its breakdown pathways

Tsutomu Hatano, Takayo Ohyabu, Takashi Yoshida

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Three new compounds, in addition to previously reported compounds, were isolated from a product mixture obtained on incubating (-)-epigallocatechin gallate (EGCG) in neutral solution. The products were two monomeric (EGCG-MOx-M3 and EGCG-MOx-M4) and one dimeric (EGCG-MOx-D4) structure involving the flavan skeleton. Possible oxidation-reduction pathways producing drastic changes in the structure of EGCG were presented based on the structures of the breakdown products.

Original language	English
Pages (from-to)	303-310
Number of pages	8
Journal	Heterocycles
Volume	65
Issue number	2
DOIs	https://doi.org/10.3987/COM-04-10259
Publication status	Published - Feb 1 2005

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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abstract = "Three new compounds, in addition to previously reported compounds, were isolated from a product mixture obtained on incubating (-)-epigallocatechin gallate (EGCG) in neutral solution. The products were two monomeric (EGCG-MOx-M3 and EGCG-MOx-M4) and one dimeric (EGCG-MOx-D4) structure involving the flavan skeleton. Possible oxidation-reduction pathways producing drastic changes in the structure of EGCG were presented based on the structures of the breakdown products.",

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AB - Three new compounds, in addition to previously reported compounds, were isolated from a product mixture obtained on incubating (-)-epigallocatechin gallate (EGCG) in neutral solution. The products were two monomeric (EGCG-MOx-M3 and EGCG-MOx-M4) and one dimeric (EGCG-MOx-D4) structure involving the flavan skeleton. Possible oxidation-reduction pathways producing drastic changes in the structure of EGCG were presented based on the structures of the breakdown products.

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The structural variation in the incubation products of (-)-epigallocatechin gallate in neutral solution suggests its breakdown pathways

Abstract

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