The role of echocardiography in predicting responders to cardiac resynchronization therapy - Results from the Japan cardiac resynchronization therapy registry trial (J-CRT)

Yoshihiro Seo, Hiroshi Itoh, Satoshi Nakatani, Mitsuaki Takami, Shigeto Naito, Tsuyoshi Shiga, Kenji Ando, Yuji Wakayama, Kazutaka Aonuma

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

Background: This multicenter prospective cohort study aimed to identify both ability of echocardiographic parameters to detect cardiac resynchronization therapy (CRT) volume responders and relation of these parameters with clinical outcomes. Methods and Results: CRT responder was defined as ≥15% reduction of left ventricular (LV) end-systolic volume at 6 months. Seven echocardiographic dyssynchrony parameters were evaluated. The clinical endpoint comprised time to death from any cause or unplanned hospitalization for a major cardiovascular event. Of the 217 patients enrolled, 63 percent were classified as volume responders, in whom significantly fewer events occurred than in non-responders (log rank, P

Original languageEnglish
Pages (from-to)1156-1163
Number of pages8
JournalCirculation Journal
Volume75
Issue number5
DOIs
Publication statusPublished - May 2011

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Cardiac Resynchronization Therapy
Registries
Echocardiography
Japan
Stroke Volume
Cause of Death
Hospitalization
Cohort Studies
Prospective Studies

Keywords

  • Cardiac resynchronization therapy
  • Echocardiography
  • Heart failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The role of echocardiography in predicting responders to cardiac resynchronization therapy - Results from the Japan cardiac resynchronization therapy registry trial (J-CRT). / Seo, Yoshihiro; Itoh, Hiroshi; Nakatani, Satoshi; Takami, Mitsuaki; Naito, Shigeto; Shiga, Tsuyoshi; Ando, Kenji; Wakayama, Yuji; Aonuma, Kazutaka.

In: Circulation Journal, Vol. 75, No. 5, 05.2011, p. 1156-1163.

Research output: Contribution to journalArticle

Seo, Yoshihiro ; Itoh, Hiroshi ; Nakatani, Satoshi ; Takami, Mitsuaki ; Naito, Shigeto ; Shiga, Tsuyoshi ; Ando, Kenji ; Wakayama, Yuji ; Aonuma, Kazutaka. / The role of echocardiography in predicting responders to cardiac resynchronization therapy - Results from the Japan cardiac resynchronization therapy registry trial (J-CRT). In: Circulation Journal. 2011 ; Vol. 75, No. 5. pp. 1156-1163.
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