The role of DNA methylation in transposable element silencing and genomic imprinting

Yoko Ikeda, Taisuke Nishimura

Research output: Chapter in Book/Report/Conference proceedingChapter

14 Citations (Scopus)

Abstract

Recent studies in molecular genetics and genomics have shown the significance of DNA methylation in transposable element (TE) silencing and genomic imprinting in plants. Transcriptional silencing of TEs is maintained ubiquitously by DNA methylation, whereas repressing transposition of TEs requires additional and specific mechanisms. The host genome utilizes RNA-directed DNA methylation (RdDM) to repress TEs that is activated by transient loss of DNA methylation. In pollen vegetative cell and female central cell, which are companion cells in plant reproduction, DNA demethylation is observed and causes small interfering RNA (siRNA) accumulation. siRNAs are supposed to be the source of TE silencing in the sperm and egg cells by RdDM. Meanwhile, DNA demethylation in the central cell causes genomic imprinting. In plants, genomic imprinting is observed in the endosperm and controls seed development. Molecular action of DNA methylation in TE silencing and genomic imprinting will be applied to understanding that in developmental processes and environmental response.

Original languageEnglish
Title of host publicationNuclear Functions in Plant Transcription, Signaling and Development
PublisherSpringer New York
Pages13-29
Number of pages17
ISBN (Print)9781493923861, 9781493923854
DOIs
Publication statusPublished - Jan 1 2015

Fingerprint

Genomic Imprinting
DNA Transposable Elements
genomic imprinting
DNA methylation
DNA Methylation
transposons
RNA
Plant DNA
Endosperm
plant reproduction
transposition (genetics)
vegetative cells
DNA
small interfering RNA
Genomics
Pollen
ova
seed development
molecular genetics
Small Interfering RNA

Keywords

  • DNA methylation/demethylation
  • Epigenetic regulation
  • Genomic imprinting
  • RNA-directed DNA methylation
  • Transposable element

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Ikeda, Y., & Nishimura, T. (2015). The role of DNA methylation in transposable element silencing and genomic imprinting. In Nuclear Functions in Plant Transcription, Signaling and Development (pp. 13-29). Springer New York. https://doi.org/10.1007/978-1-4939-2386-1_2

The role of DNA methylation in transposable element silencing and genomic imprinting. / Ikeda, Yoko; Nishimura, Taisuke.

Nuclear Functions in Plant Transcription, Signaling and Development. Springer New York, 2015. p. 13-29.

Research output: Chapter in Book/Report/Conference proceedingChapter

Ikeda, Y & Nishimura, T 2015, The role of DNA methylation in transposable element silencing and genomic imprinting. in Nuclear Functions in Plant Transcription, Signaling and Development. Springer New York, pp. 13-29. https://doi.org/10.1007/978-1-4939-2386-1_2
Ikeda Y, Nishimura T. The role of DNA methylation in transposable element silencing and genomic imprinting. In Nuclear Functions in Plant Transcription, Signaling and Development. Springer New York. 2015. p. 13-29 https://doi.org/10.1007/978-1-4939-2386-1_2
Ikeda, Yoko ; Nishimura, Taisuke. / The role of DNA methylation in transposable element silencing and genomic imprinting. Nuclear Functions in Plant Transcription, Signaling and Development. Springer New York, 2015. pp. 13-29
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