Abstract
A 50-year-old woman with epigastric discomfort was referred to our hospital. Esophagogastroduodenoscopy showed flat, elevated, submucosal tumor-like lesions in the esophagus. Extranodal marginal zone lymphoma of the mucosa-associated lymphoid tissue (MALT lymphoma) of the esophagus was diagnosed based on the examination of an endoscopic biopsy specimen. Computed tomography showed the enlargement of a lymph node in the gastric cardia. The present case showed disease progression despite Helicobacter pylori eradication therapy and achieved partial remission after rituximab monotherapy. The patient remained in partial remission for 20 months. This case suggests that esophageal MALT lymphoma with lymph node involvement does not respond to H. pylori eradication therapy and that it requires systemic treatment.
Original language | English |
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Pages (from-to) | 207-212 |
Number of pages | 6 |
Journal | Internal Medicine |
Volume | 58 |
Issue number | 2 |
DOIs | |
Publication status | Published - Jan 15 2019 |
Externally published | Yes |
Keywords
- Eradication therapy
- Esophagus
- Helicobacter pylori
- MALT
- Rituximab
ASJC Scopus subject areas
- Internal Medicine