Abstract
Objective It is sometimes difficult to determine during the preoperative period whether patients have oral infections; these patients need treatment to prevent oral infection–related complications from arising during medical therapies, such as cancer therapy and surgery. One of the reasons for this difficulty is that basic medical tests do not identify oral infections, including periodontitis and periapical periodontitis. In this report, we investigated the potential of positron emission tomography/computerized tomography (PET/CT) as a diagnostic tool in these patients. Study Design We evaluated eight patients during the preoperative period. All patients underwent PET/CT scanning and were identified as having the signs of oral infection, as evidenced by 18F-fludeoxyglucose (FDG) localization in the oral regions. Periodontal examination and orthopantomogram evaluation showed severe infection or bone resorption in the oral regions. Results 18F-FDG was localized in oral lesions, such as severe periodontitis, apical periodontitis, and pericoronitis of the third molar. The densities of 18F-FDG were proportional to the degree of inflammation. Conclusions PET/CT is a potential diagnostic tool for oral infections. It may be particularly useful in patients during preoperative staging, as they frequently undergo scanning at this time, and those identified as having oral infections at this time require treatment before cancer therapy or surgery.
| Original language | English |
|---|---|
| Pages (from-to) | 242-249 |
| Number of pages | 8 |
| Journal | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology |
| Volume | 122 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Aug 1 2016 |
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ASJC Scopus subject areas
- Surgery
- Pathology and Forensic Medicine
- Oral Surgery
- Dentistry (miscellaneous)
- Radiology Nuclear Medicine and imaging
Cite this
The potential of positron emission tomography/computerized tomography (PET/CT) scanning as a detector of high-risk patients with oral infection during preoperative staging. / Yamashiro, Keisuke; Nakano, Makoto; Sawaki, Koichi; Okazaki, Fumihiko; Hirata, Yasuhisa; Takashiba, Shogo.
In: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Vol. 122, No. 2, 01.08.2016, p. 242-249.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The potential of positron emission tomography/computerized tomography (PET/CT) scanning as a detector of high-risk patients with oral infection during preoperative staging
AU - Yamashiro, Keisuke
AU - Nakano, Makoto
AU - Sawaki, Koichi
AU - Okazaki, Fumihiko
AU - Hirata, Yasuhisa
AU - Takashiba, Shogo
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Objective It is sometimes difficult to determine during the preoperative period whether patients have oral infections; these patients need treatment to prevent oral infection–related complications from arising during medical therapies, such as cancer therapy and surgery. One of the reasons for this difficulty is that basic medical tests do not identify oral infections, including periodontitis and periapical periodontitis. In this report, we investigated the potential of positron emission tomography/computerized tomography (PET/CT) as a diagnostic tool in these patients. Study Design We evaluated eight patients during the preoperative period. All patients underwent PET/CT scanning and were identified as having the signs of oral infection, as evidenced by 18F-fludeoxyglucose (FDG) localization in the oral regions. Periodontal examination and orthopantomogram evaluation showed severe infection or bone resorption in the oral regions. Results 18F-FDG was localized in oral lesions, such as severe periodontitis, apical periodontitis, and pericoronitis of the third molar. The densities of 18F-FDG were proportional to the degree of inflammation. Conclusions PET/CT is a potential diagnostic tool for oral infections. It may be particularly useful in patients during preoperative staging, as they frequently undergo scanning at this time, and those identified as having oral infections at this time require treatment before cancer therapy or surgery.
AB - Objective It is sometimes difficult to determine during the preoperative period whether patients have oral infections; these patients need treatment to prevent oral infection–related complications from arising during medical therapies, such as cancer therapy and surgery. One of the reasons for this difficulty is that basic medical tests do not identify oral infections, including periodontitis and periapical periodontitis. In this report, we investigated the potential of positron emission tomography/computerized tomography (PET/CT) as a diagnostic tool in these patients. Study Design We evaluated eight patients during the preoperative period. All patients underwent PET/CT scanning and were identified as having the signs of oral infection, as evidenced by 18F-fludeoxyglucose (FDG) localization in the oral regions. Periodontal examination and orthopantomogram evaluation showed severe infection or bone resorption in the oral regions. Results 18F-FDG was localized in oral lesions, such as severe periodontitis, apical periodontitis, and pericoronitis of the third molar. The densities of 18F-FDG were proportional to the degree of inflammation. Conclusions PET/CT is a potential diagnostic tool for oral infections. It may be particularly useful in patients during preoperative staging, as they frequently undergo scanning at this time, and those identified as having oral infections at this time require treatment before cancer therapy or surgery.
UR - http://www.scopus.com/inward/record.url?scp=84991585658&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84991585658&partnerID=8YFLogxK
U2 - 10.1016/j.oooo.2016.04.006
DO - 10.1016/j.oooo.2016.04.006
M3 - Article
C2 - 27422423
AN - SCOPUS:84991585658
VL - 122
SP - 242
EP - 249
JO - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
JF - Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
SN - 2212-4403
IS - 2
ER -