The pathophysiological mechanism underlying Brugada syndrome. Depolarization versus repolarization

Arthur A.M. Wilde, Pieter G. Postema, José M. Di Diego, Sami Viskin, Hiroshi Morita, Jeffrey M. Fish, Charles Antzelevitch

Research output: Contribution to journalComment/debatepeer-review

255 Citations (Scopus)

Abstract

This Point/Counterpoint presents a scholarly debate of the mechanisms underlying the electrocardiographic and arrhythmic manifestations of Brugada syndrome (BrS), exploring in detail the available evidence in support of the repolarization vs. depolarization hypothesis.

Original languageEnglish
Pages (from-to)543-553
Number of pages11
JournalJournal of Molecular and Cellular Cardiology
Volume49
Issue number4
DOIs
Publication statusPublished - Oct 2010

Keywords

  • Brugada syndrome
  • Depolarization versus repolarization

ASJC Scopus subject areas

  • Molecular Biology
  • Cardiology and Cardiovascular Medicine

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