The mutual sparing effects of selenium and vitamin E in animal nutrition may be further explained by the discovery that mamalian thioredoxin reductase is a selenoenzyme

Takashi Tamura, V. Gladyshev, S. Y. Liu, T. C. Stadtman

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

The recent discovery that mammalian thioredoxin reductase is a selenoprotein furnishes an additional explanation of the mutual sparing roles of selenium and vitamin E in cellular antioxidant systems. Thioredoxin reductases isolated from human lung adenocarcinoma cells, human Jurkat T-cells and HeLa cells contain selenocysteine which is located in a C-terminal tripeptide, -Cys-SeCys-Gly.

Original languageEnglish
Pages (from-to)99-102
Number of pages4
JournalBioFactors
Volume5
Issue number2
Publication statusPublished - 1995
Externally publishedYes

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Thioredoxin-Disulfide Reductase
Nutrition
Selenium
Vitamin E
Animals
Selenoproteins
Selenocysteine
Jurkat Cells
T-cells
HeLa Cells
Antioxidants
T-Lymphocytes
Adenocarcinoma of lung

ASJC Scopus subject areas

  • Biochemistry

Cite this

The mutual sparing effects of selenium and vitamin E in animal nutrition may be further explained by the discovery that mamalian thioredoxin reductase is a selenoenzyme. / Tamura, Takashi; Gladyshev, V.; Liu, S. Y.; Stadtman, T. C.

In: BioFactors, Vol. 5, No. 2, 1995, p. 99-102.

Research output: Contribution to journalArticle

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