The multicentric epitheloid hemangioendothelioma of bone: A case example and review of the literature

G. Gosheger, J. Hardes, Toshihumi Ozaki, E. Horst, H. Bürger, W. Winkelmann

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Epitheloid hemangioendothelioma of bone is a rare primary bone malignancy. Diagnosis can be difficult for physicians who are not experienced with bone neoplasms. We also had difficulties in diagnosis and treatment in one of our patients with a multicentric epitheloid hemangioendothelioma involving the pelvis, left femur, and left tibia. We recommend a complete skeletal survey with magnetic resonance imaging because it can reveal previously undetected lesions on conventional radiographs. We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. The femur was replaced by a modular endoprosthesis. The patient is provided with an aboveknee prosthesis and is able to walk even longer distances with a cane 2 years after surgery. In our opinion it is necessary to perform a wide resection of this tumour in order to treat a patient with curative intention. Palliative radiotherapy should only be used for a non-resectable tumour or in metastatic disease. Chemotherapy is not a treatment option.

Original languageEnglish
Pages (from-to)11-18
Number of pages8
JournalJournal of Cancer Research and Clinical Oncology
Volume128
Issue number1
DOIs
Publication statusPublished - 2002
Externally publishedYes

Fingerprint

Hemangioendothelioma
Femur
Bone and Bones
Bone Neoplasms
Neoplasms
Canes
Hip Joint
Pelvis
Tibia
Amputation
Prostheses and Implants
Leg
Radiotherapy
Magnetic Resonance Imaging
Physicians
Drug Therapy
Therapeutics

Keywords

  • Amputation
  • Endoprosthesis
  • Hemangioendothelioma

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

The multicentric epitheloid hemangioendothelioma of bone : A case example and review of the literature. / Gosheger, G.; Hardes, J.; Ozaki, Toshihumi; Horst, E.; Bürger, H.; Winkelmann, W.

In: Journal of Cancer Research and Clinical Oncology, Vol. 128, No. 1, 2002, p. 11-18.

Research output: Contribution to journalArticle

Gosheger, G. ; Hardes, J. ; Ozaki, Toshihumi ; Horst, E. ; Bürger, H. ; Winkelmann, W. / The multicentric epitheloid hemangioendothelioma of bone : A case example and review of the literature. In: Journal of Cancer Research and Clinical Oncology. 2002 ; Vol. 128, No. 1. pp. 11-18.
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