Abstract
Epitheloid hemangioendothelioma of bone is a rare primary bone malignancy. Diagnosis can be difficult for physicians who are not experienced with bone neoplasms. We also had difficulties in diagnosis and treatment in one of our patients with a multicentric epitheloid hemangioendothelioma involving the pelvis, left femur, and left tibia. We recommend a complete skeletal survey with magnetic resonance imaging because it can reveal previously undetected lesions on conventional radiographs. We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. The femur was replaced by a modular endoprosthesis. The patient is provided with an aboveknee prosthesis and is able to walk even longer distances with a cane 2 years after surgery. In our opinion it is necessary to perform a wide resection of this tumour in order to treat a patient with curative intention. Palliative radiotherapy should only be used for a non-resectable tumour or in metastatic disease. Chemotherapy is not a treatment option.
| Original language | English |
|---|---|
| Pages (from-to) | 11-18 |
| Number of pages | 8 |
| Journal | Journal of Cancer Research and Clinical Oncology |
| Volume | 128 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2002 |
| Externally published | Yes |
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Keywords
- Amputation
- Endoprosthesis
- Hemangioendothelioma
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
The multicentric epitheloid hemangioendothelioma of bone : A case example and review of the literature. / Gosheger, G.; Hardes, J.; Ozaki, Toshihumi; Horst, E.; Bürger, H.; Winkelmann, W.
In: Journal of Cancer Research and Clinical Oncology, Vol. 128, No. 1, 2002, p. 11-18.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The multicentric epitheloid hemangioendothelioma of bone
T2 - A case example and review of the literature
AU - Gosheger, G.
AU - Hardes, J.
AU - Ozaki, Toshihumi
AU - Horst, E.
AU - Bürger, H.
AU - Winkelmann, W.
PY - 2002
Y1 - 2002
N2 - Epitheloid hemangioendothelioma of bone is a rare primary bone malignancy. Diagnosis can be difficult for physicians who are not experienced with bone neoplasms. We also had difficulties in diagnosis and treatment in one of our patients with a multicentric epitheloid hemangioendothelioma involving the pelvis, left femur, and left tibia. We recommend a complete skeletal survey with magnetic resonance imaging because it can reveal previously undetected lesions on conventional radiographs. We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. The femur was replaced by a modular endoprosthesis. The patient is provided with an aboveknee prosthesis and is able to walk even longer distances with a cane 2 years after surgery. In our opinion it is necessary to perform a wide resection of this tumour in order to treat a patient with curative intention. Palliative radiotherapy should only be used for a non-resectable tumour or in metastatic disease. Chemotherapy is not a treatment option.
AB - Epitheloid hemangioendothelioma of bone is a rare primary bone malignancy. Diagnosis can be difficult for physicians who are not experienced with bone neoplasms. We also had difficulties in diagnosis and treatment in one of our patients with a multicentric epitheloid hemangioendothelioma involving the pelvis, left femur, and left tibia. We recommend a complete skeletal survey with magnetic resonance imaging because it can reveal previously undetected lesions on conventional radiographs. We performed an extraarticular resection of the hip joint including the spina iliaca anterior inferior, resection of the femur, and amputation of the lower leg. The femur was replaced by a modular endoprosthesis. The patient is provided with an aboveknee prosthesis and is able to walk even longer distances with a cane 2 years after surgery. In our opinion it is necessary to perform a wide resection of this tumour in order to treat a patient with curative intention. Palliative radiotherapy should only be used for a non-resectable tumour or in metastatic disease. Chemotherapy is not a treatment option.
KW - Amputation
KW - Endoprosthesis
KW - Hemangioendothelioma
UR - http://www.scopus.com/inward/record.url?scp=0036177077&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036177077&partnerID=8YFLogxK
U2 - 10.1007/s004320100285
DO - 10.1007/s004320100285
M3 - Article
C2 - 11862467
AN - SCOPUS:0036177077
VL - 128
SP - 11
EP - 18
JO - Journal of Cancer Research and Clinical Oncology
JF - Journal of Cancer Research and Clinical Oncology
SN - 0171-5216
IS - 1
ER -