The maximum standardized uptake value is more reliable than size measurement in early follow-up to evaluate potential pulmonary malignancies following radiofrequency ablation

Aierken Alafate, Takayoshi Shinya, Yoshihiro Okumura, Shuhei Sato, Takao Hiraki, Hiroaki Ishii, Hideo Gobara, Katsuya Kato, Toshiyoshi Fujiwara, Shinichiro Miyoshi, Mitsumasa Kaji, Susumu Kanazawa

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7 Citations (Scopus)


We retrospectively evaluated the accumulation of fluorodeoxy glucose (FDG) in pulmonary malignancies without local recurrence during 2-year follow-up on positron emission tomography (PET)/com-puted tomography (CT) after radiofrequency ablation (RFA). Thirty tumors in 25 patients were studied (10 non-small cell lung cancers; 20 pulmonary metastatic tumors). PET/CT was performed before RFA, 3 months after RFA, and 6 months after RFA. We assessed the FDG accumulation with the maximum standardized uptake value (SUVmax) compared with the diameters of the lesions. The SUVmax had a decreasing tendency in the first 6 months and, at 6 months post-ablation, FDG accumulation was less affected by inflammatory changes than at 3 months post-RFA. The diameter of the ablated lesion exceeded that of the initial tumor at 3 months post-RFA and shrank to pre-ablation dimensions by 6 months post-RFA. SUVmax was more reliable than the size measurements by CT in the first 6 months after RFA, and PET/CT at 6 months post-RFA may be more appropriate for the assessment of FDG accumulation than that at 3 months post-RFA.

Original languageEnglish
Pages (from-to)105-112
Number of pages8
JournalActa Medica Okayama
Issue number2
Publication statusPublished - 2013



  • Fluorodeoxy glucose (FDG)
  • Non-small cell lung cancer (NSCLC)
  • Positron emission tomography (PET)
  • Radiofrequency ablation (RFA)
  • Standardized uptake value (SUV)

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

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