The first case of non-leukemic sarcoma composed of mixed-phenotype acute leukemia, B/myeloid, not otherwise specified

Teruhito Takakuwa, Takahiko Nakane, Masahiko Ohsawa, Joji Nagasaki, Yasutaka Aoyama, Mistutaka Nishimoto, Yoshiki Hayashi, Yuko Kuwae, Masayuki Hino, Hirohisa Nakamae

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Isolated sarcoma with features of mixed-phenotype acute leukemia (MPAL) is an extremely rare disease and it can be easily misdiagnosed as lymphoma or other malignancies. We herein report the case of a 61-year-old woman with non-leukemic sarcoma of the right pleura, pretracheal lymph node, and supraclavicular lymph node with features of MPAL, B/myeloid, not otherwise specified, which was first misdiagnosed as diffuse large B cell lymphoma. After performing a detailed re-examination of the biopsy specimens, few scattered eosinophilic myelocytes allowed us to reach a correct diagnosis of MPAL and the patient was thereafter successfully treated by intensified chemotherapy followed by cord blood transplantation.

Original languageEnglish
Pages (from-to)1155-1158
Number of pages4
JournalInternal Medicine
Volume57
Issue number8
DOIs
Publication statusPublished - 2018
Externally publishedYes

Keywords

  • Chemotherapy
  • Diagnosis
  • Mixed-phenotype acute leukemia
  • Sarcoma
  • Stem cell transplantation

ASJC Scopus subject areas

  • Internal Medicine

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