The effect of mechanical property change of the viscoelastic tube on the characteristic of the arterial stiffness indexes. – Consideration based on numerical simulation –

Tomoki Kitawaki, M. Shimizu, H. Oka, R. Himeno

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Recently, Arterial Stiffness has attracted a great deal of attention as the predictor of the circulatory system condition. The Arterial Stiffness indexes (Pulse Wave Velocity: PWV, pulse wave shape index (AIx: Augmentation Index), Pulse Pressure: PP, Mean Arterial Pressure: MAP, etc.), seem to show the change of the static stiffness. However, the pulse wave has the periodic beating in vivo, it is considered that Arterial Stiffness index is influenced not only the static stiffness but also dynamic viscoelastic modulus or peripheral resistance. Accordingly, the analysis was carried out by using numerical simulation, to understand the effect of the difference of such mechanical property on the pulse wave propagation and the Arterial Stiffness indexes. A single cylindrical tube was constructed by the model of the systemic artery from central aorta to common iliac artery bifurcation. When the ideal beating of periodic pressure pulse wave were given at the input, pulse pressure conditions were calculated. The vascular elastic modulus, the viscoelastic modulus and peripheral resistance were changed independently. Following results were obtained. 1) By the increase in the vascular elastic and the viscoelastic modulus, the wave reflection from peripheral was increased, and then the PP and PWV increase. 2) By the increase in the peripheral resistance, the AIx and MAP increase although the PP does not change. From these results, following conclusions were obtained. 3) The change of PWV shows the change of vascular elasticity and viscoelasticity of the thick artery, and it similarly changes by the aging with the PP. 4) The AIx value gradually increase by the aging, similarly with the MAP.

Original languageEnglish
Title of host publicationIFMBE Proceedings
EditorsSun I. Kim, Tae Suk Suh
PublisherSpringer Verlag
Pages3488-3491
Number of pages4
Edition1
ISBN (Print)9783540368397
DOIs
Publication statusPublished - Jan 1 2007
Event10th World Congress on Medical Physics and Biomedical Engineering, WC 2006 - Seoul, Korea, Republic of
Duration: Aug 27 2006Sep 1 2006

Publication series

NameIFMBE Proceedings
Number1
Volume14
ISSN (Print)1680-0737
ISSN (Electronic)1433-9277

Other

Other10th World Congress on Medical Physics and Biomedical Engineering, WC 2006
CountryKorea, Republic of
CitySeoul
Period8/27/069/1/06

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Keywords

  • Artery
  • Bio-fluid mechanics
  • Blood flow
  • Computational fluid dynamics
  • Viscoelasticity

ASJC Scopus subject areas

  • Bioengineering
  • Biomedical Engineering

Cite this

Kitawaki, T., Shimizu, M., Oka, H., & Himeno, R. (2007). The effect of mechanical property change of the viscoelastic tube on the characteristic of the arterial stiffness indexes. – Consideration based on numerical simulation –. In S. I. Kim, & T. S. Suh (Eds.), IFMBE Proceedings (1 ed., pp. 3488-3491). (IFMBE Proceedings; Vol. 14, No. 1). Springer Verlag. https://doi.org/10.1007/978-3-540-36841-0_882